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1. • Comfort Suites Jackson/Cape Girardeau

     Hotel · 401.47mi

     Open · 172 on TripAdvisor

     2904 S Old Orchard Rd · (573) 204-0014
     
   • Town House Inn, Jackson, MO 63755

     Hotel, Inn · 403.37mi

     Open · 8 on TripAdvisor

     517 E Jackson Blvd · (573) 243-3577
     
   • La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

     Hotel

     44 on TripAdvisor

     3003 S Old Orchard Rd · (573) 987-5501
     
   • Jackson-Days Inn

     Motel

     1 on TripAdvisor

     517 US-61 · (800) 544-8313
   • Best Western Plus

     Hotel · 401.69mi

     Open · 1 on TripAdvisor

     3003 S Old Orchard Rd · (573) 987-5501
   • Quality Inn

     Hotel · 400.73mi

     Open · 433 on TripAdvisor

     2011 N Kingshighway St · (573) 339-0808
     
   • Drury Inn & Suites Cape Girardeau

     Hotel · 401.9mi

     Open · 284 on TripAdvisor

     3303 Campster Dr · (573) 339-9500
     
   • Drury Inn & Suites Jackson, MO

     Hotel · 400.61mi

     Open · 297 on TripAdvisor

     225 Drury Ln · (573) 243-9200
     
   • Drury Plaza Hotel Cape Girardeau Conference Center

     Hotel

     175 on TripAdvisor

     3351 Percy Dr · (573) 334-7151
     
   • Auburn Place Hotel & Suites

     Motel, Hotel

     531 on TripAdvisor

     3265 William St · (573) 651-4486
     
   • Candlewood Suites Cape Girardeau, an IHG Hotel

     Hotel, Conference Center · 401.92mi

     Open · 142 on TripAdvisor

     485 S Mt Auburn Rd · (573) 334-6868
     
   • Town House Inn Cape Girardeau

     Hotel

     47 on TripAdvisor

     505 N Kingshighway · (573) 335-2700
     
   • Super 8 by Wyndham Cape Girardeau

     Hotel · $

     5 on Yelp

     2011 N Kingshighway · (573) 339-0808
     
   • Holiday Inn Express & Suites Cape Girardeau I-55, an IHG Hotel

     Hotel · 401.71mi

     Open · 352 on TripAdvisor

     3253 William St · (573) 334-4491
     
   • Pear Tree Inn Cape Girardeau Near the Medical Center

     Hotel · 401.59mi

     Open · 229 on TripAdvisor

     3248 William St · (573) 334-3000