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1. • Quality Inn Charleston I-57

     Hotel · 405.45mi

     Open · 78 on TripAdvisor

     102 Drake St · (573) 683-4200
     
   • Super 8 by Wyndham Charleston MO

     Hotel, Motel

     275 on TripAdvisor

     310 S Story St · (573) 427-2004
     
   • Eagle Inn

     Motel, Hotel · 402.92mi

     Open · 22 on TripAdvisor

     2811 E Marshall St · (573) 683-3900
     
   • Drury Inn & Suites Sikeston

     Hotel · 414.52mi

     Open · 506 on TripAdvisor

     2608 E Malone St · (573) 472-2299
     
   • Best Western Plus Sikeston

     Hotel · 414.31mi

     Open · 499 on TripAdvisor

     120 S Interstate Dr · (573) 481-9500
     
   • Comfort Inn & Suites Sikeston I-55

     Hotel · 414.67mi

     Open · 142 on TripAdvisor

     109 Matthews Ln · (573) 472-0197
     
   • Pear Tree Inn Sikeston

     Hotel · 414.6mi

     Open · 417 on TripAdvisor

     2602 E Malone St · (573) 471-4100
     
   • Travel Inn and Suites

     Hotel · 414.6mi

     Open · 10 on TripAdvisor

     100 Matthews Ln · (573) 621-4999
     
   • Americas Best Value Inn & Suites Sikeston

     Hotel

     4 on Yelp

     220 S Interstate Dr · (573) 471-9700
     
   • Motel 6

     Hotel, Motel · 414.28mi

     Open

     110 S Interstate Dr · (573) 471-7400
     
   • Days Inn

     Hotel, Motel

     13201 Kessler Rd · (618) 734-0215
   • Hampton Inn Sikeston

     Hotel · 418.3mi

     Open · 116 on TripAdvisor

      · (573) 621-4100
     
   • Super 8 by Wyndham Sikeston/Miner Area

     Hotel, Motel

     387 on TripAdvisor

     2609 E Malone St · (573) 471-7944
     
   • Drury Inn & Suites Cape Girardeau

     Hotel · 401.9mi

     Open · 284 on TripAdvisor

     3303 Campster Dr · (573) 339-9500
     
   • Drury Plaza Hotel Cape Girardeau Conference Center

     Hotel

     175 on TripAdvisor

     3351 Percy Dr · (573) 334-7151