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1. • Hampton Inn Sikeston

     Hotel · 418.3mi

     Open · 116 on TripAdvisor

      · (573) 621-4100
     
   • Drury Inn & Suites Sikeston

     Hotel · 414.52mi

     Open · 506 on TripAdvisor

     2608 E Malone St · (573) 472-2299
     
   • Pear Tree Inn Sikeston

     Hotel · 414.6mi

     Open · 417 on TripAdvisor

     2602 E Malone St · (573) 471-4100
     
   • Holiday Inn Express & Suites Sikeston, an IHG Hotel

     Hotel · 417.92mi

     Open · 129 on TripAdvisor

     115 Hospitality Dr · (573) 475-9522
     
   • Comfort Inn & Suites Sikeston I-55

     Hotel · 414.67mi

     Open · 142 on TripAdvisor

     109 Matthews Ln · (573) 472-0197
     
   • Best Western Plus Sikeston

     Hotel · 414.31mi

     Open · 499 on TripAdvisor

     120 S Interstate Dr · (573) 481-9500
     
   • Travel Inn and Suites

     Hotel · 414.6mi

     Open · 10 on TripAdvisor

     100 Matthews Ln · (573) 621-4999
     
   • Americas Best Value Inn & Suites Sikeston

     Hotel

     4 on Yelp

     220 S Interstate Dr · (573) 471-9700
     
   • Hampton Inn by Hilton

     Hotel, Motel

     914 Davis Blvd · (573) 475-8410
   • Days Inn and Suites by Wyndham Sikeston

     Hotel, Inn · 414.41mi

     Open · 235 on TripAdvisor

     220 S Interstate Dr · (573) 471-9700
     
   • Super 8 by Wyndham Sikeston/Miner Area

     Hotel, Motel

     387 on TripAdvisor

     2609 E Malone St · (573) 471-7944
     
   • Country Hearth Inns & Suites - Sikeston

     Hotel · $$

     8 on Yelp

     100 Matthews Ln · (573) 472-4400
     
   • Motel 6

     Hotel, Motel · 414.28mi

     Open

     110 S Interstate Dr · (573) 471-7400
     
   • Country Yard Inn and Suites

     Motel · 414.28mi

     Open · 1 on TripAdvisor

     I-55 & E Malone St · (573) 471-7400
   • Econo Lodge

     Hotel · $$ · 438.01mi

     Open · 8 on Yelp

     913 Outer Rd · (573) 624-7400