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1. • Travel Inn and Suites

     Hotel · 414.6mi

     Open · 10 on TripAdvisor

     100 Matthews Ln · (573) 621-4999
     
   • Pear Tree Inn Sikeston

     Hotel · 414.6mi

     Open · 414 on TripAdvisor

     2602 E Malone St · (573) 471-4100
     
   • Drury Inn & Suites Sikeston

     Hotel · 414.52mi

     Open · 506 on TripAdvisor

     2608 E Malone St · (573) 472-2299
     
   • Econo Lodge

     Hotel · $$ · 438.01mi

     Open · 8 on Yelp

     913 Outer Rd · (573) 624-7400
     
   • Drury Plaza Hotel Cape Girardeau Conference Center

     Hotel

     174 on TripAdvisor

     3351 Percy Dr · (573) 334-7151
     
   • Auburn Place Hotel & Suites

     Motel, Hotel

     531 on TripAdvisor

     3265 William St · (573) 651-4486
     
   • Candlewood Suites Cape Girardeau, an IHG Hotel

     Hotel, Conference Center · 401.92mi

     Open · 142 on TripAdvisor

     485 S Mt Auburn Rd · (573) 334-6868
     
   • Comfort Inn & Suites Sikeston I-55

     Hotel · 414.67mi

     Open · 141 on TripAdvisor

     109 Matthews Ln · (573) 472-0197
     
   • Best Western Plus Sikeston

     Hotel · 414.31mi

     Open · 498 on TripAdvisor

     120 S Interstate Dr · (573) 481-9500
     
   • Drury Inn & Suites Cape Girardeau

     Hotel · 401.9mi

     Open · 283 on TripAdvisor

     3303 Campster Dr · (573) 339-9500
     
   • Hampton Inn by Hilton

     Hotel, Motel

     914 Davis Blvd · (573) 475-8410
   • Holiday Inn Express & Suites Cape Girardeau I-55, an IHG Hotel

     Hotel · 401.71mi

     Open · 352 on TripAdvisor

     3253 William St · (573) 334-4491
     
   • Eagle Inn

     Motel, Hotel · 402.92mi

     Open · 22 on TripAdvisor

     2811 E Marshall St · (573) 683-3900
     
   • Holiday Inn Express & Suites Sikeston, an IHG Hotel

     Hotel · 417.92mi

     Open · 128 on TripAdvisor

     115 Hospitality Dr · (573) 475-9522
     
   • Days Inn

     Hotel, Motel

     13201 Kessler Rd · (618) 734-0215