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  1. Feb 17, 2020 · Includes MetroNIDAZOLE (Systemic) indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more.

  2. Feb 17, 2020 · Begin with once daily dosing (at bedtime); increase to twice daily if needed. Children 2 to <6 years: 2.5 to 3.75 mL (88 to 132 mg senna leaf extract) once or twice daily; maximum daily dose: 7.5 mL/ day. Children ≥6 years to <12 years: 5 to 7.5 mL (176 to 264 mg senna leaf extract) once or twice daily; maximum daily dose: 15 mL/ day.

  3. Feb 9, 2020 · Dosing should start at the lower end of dosing range and be titrated to response due to possible increased incidence of hepatic, renal, or cardiac impairment. Elderly patients also show decreased clearance of amlodipine. Chronic stable angina (alternative agent); vasospastic angina: Oral: Initial: 5 mg once daily.

  4. Feb 17, 2020 · Urine (10% as norfluoxetine, 2.5% to 5% as fluoxetine) Onset of Action. Depression: The onset of action is within a week; however, individual response varies greatly and full response may not be seen until 8 to 12 weeks after initiation of treatment. Time to Peak. Serum: 6 to 8 hours. Half-Life Elimination

  5. Feb 17, 2020 · Usual dosage range: Immediate release: Oral: 500 mg to 1 g every 8 to 12 hours. Extended release: 775 mg once daily. Actinomycosis (off-label use): Note: For initial therapy of mild infections or step-down therapy following parenteral treatment of severe infections.

  6. Feb 17, 2020 · Unpremedicated patients: Initial: 0.3 to 0.35 mg/kg over 20 to 30 seconds; after 2 minutes, may repeat if necessary at ~25% of initial dose every 2 minutes, up to a total dose of 0.6 mg/kg in resistant cases. Premedicated patients: Usual dosage range: 0.05 to 0.2 mg/kg (Barash 2009; Miller 2010).

  7. Feb 9, 2020 · Patient weight ≤70 kg: Oral: Initial: ~0.5 mg/kg/day; increase after a minimum of 3 days to ~1.2 mg/kg/day; may administer either once daily in the morning or in 2 evenly divided doses and administered in the morning and late afternoon/early evening; maximum daily dose: 1.4 mg/kg/ day or 100 mg/ day, whichever is less.

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