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Feb 20, 2020 · The need for improved diagnosis of fungal infections. Early diagnosis of mycoses is decisive to efficient therapy. Common methods for the laboratory diagnosis of fungal infections include direct microscopic examination of human or animal samples, histopathology, microbial culture, antigen detection, serology, and, in a few cases, molecular ...
Jul 21, 2020 · More research is urgently needed to improve the diagnosis and prognosis of sepsis in immunocompromised patients, who frequently do not present with classic symptoms and signs of infection. More sensitive and specific microbial and host biomarkers will be necessary to further curb morbidity and mortality associated with sepsis.
Jan 4, 2011 · Infection is acquired by inhalation of spores and epidemics have occurred during construction in hospitals. The hyphae invade blood vessels causing thrombosis and infraction and can erode through facial planes, cartilage, and bone. Patients with pulmonary infection may present with symptoms suggesting acute pulmonary embolism.
May 5, 2015 · The prevention and treatment of sepsis in the immunocompromised host present a challenging array of diagnostic and management issues. The neutropenic patient has a primary defect in innate immune responses and is susceptible to conventional and opportunistic pathogens. The solid organ transplant patient has a primary defect in adaptive immunity and is susceptible to a myriad of pathogens that ...
Introduction. Older adults are at an increased risk of contracting infectious pathogens due to their declining immune system, in addition to other age-related changes throughout all body systems 1. Due to these vulnerabilities, older adults are at an increased risk of sepsis 1. Often, diagnosis and initiation of sepsis bundles are delayed due ...
The term “septic shock” is used to describe what’s happening when a person’s blood pressure is low, oxygen delivery to vital organs is compromised, and the threat of death is imminent. About 1.7 million U.S. adult cases of sepsis occur each year, and nearly 270,000 die from the condition. Sepsis can be difficult to diagnose immediately ...
Fungal infections in the immunocompromised host are difficult to diagnose and difficult to treat successfully. The diagnosis is often missed or delayed because of the non-specific clinical features, the failure to isolate or difficulty in interpreting the presence of the fungus from routine microbiological cultures, and the limited usefulness ...
