Search results
Together, the frontal regions that mediate reward, motivation, and affect regulation project primarily to the rostral striatum, including the nucleus accumbens, the medial caudate nucleus, and the medial and ventral rostral putamen, collectively referred to as the VS. The area occupies over 20% of the striatum (Haber et al. 2006).
Nov 30, 2016 · Although the study does not specifically mention it, the nucleus accumbens, and the reward system in general, are associated with the addictive triggers that tells the brain love and drug-taking ...
In the basal ganglia, activation of opioid receptors in the nucleus accumbens may be responsible for some of the pleasure associated with alcohol intoxication (see Figure 1). In addition, alcohol causes the ventral tegmental area to send dopamine signals to the nucleus accumbens.
Oct 18, 2021 · The nucleus accumbens (NAc) plays an important role in regulating multiple behaviors, and its dysfunction has been linked to many neural disorders. However, the molecular, cellular and anatomic ...
The nucleus accumbens is a major input structure of the basal ganglia and integrates information from cortical and limbic structures to mediate goal-directed behaviors. Chronic exposure to several classes of drugs of abuse disrupts plasticity in this region, allowing drug-associated cues to engender a pathologic motivation for drug seeking.
Jun 30, 2020 · The nucleus accumbens (NAc) has long been considered a key brain region for regulating many behaviors, especially those related to depression and addiction. In this review article, we focus on the association between addiction and depression, highlighting the potential mediating role of the NAc in this comorbidity via the regulation of changes ...
Feb 18, 2020 · Measurements of neuron soma size and density in rat dorsal striatum, nucleus accumbens core and nucleus accumbens shell: Differences between striatal region and brain hemisphere, but not sex ...
