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  1. Dec 4, 2009 · 2 DOSAGE AND ADMINISTRATION 2.1 Dosage in von Willebrand Disease 2.2 Dosing Schedule 2.3 Administration 3 DOSAGE FORMS AND STRENGTHS 4 CONTRAINDICATIONS 5 WARNINGS AND PRECAUTIONS 5.1 Hypersensitivity 5.2 Thromboembolic Risk 5.3 Inhibitor Formation 5.4 Infection Risk from Human Plasma 5.5 Monitoring and Laboratory Tests 6 ADVERSE REACTIONS

  2. The most serious risk of bleeding, however, generally does not occur until the platelet count falls below 10,000 to 20,000 platelets per microliter of blood (10 to 20 ×109 per liter). At these very low levels, bleeding may occur without any recognized injury. There are three main types of von Willebrand disease, all of which are inherited.

  3. Von Willebrand disease (vWD) is the most common inherited disorder of hemostasis in both humans and dogs. It is due to a deficiency or abnormality in von Willebrand factor (vWf). Production of vWf Von Willebrand factor is a large multimeric glycoprotein that circulates non-covalently with factor VIII coagulant protein. It is produced in different cells and […]

  4. Affected dogs have nosebleeds, tiny purplish red spots (petechiae), and bleeding of the gums. This disorder should be suspected in Basset Hounds that have these signs, along with normal levels of platelets and von Willebrand’s factor. Specific diagnosis of this disorder requires specialized platelet function testing.

  5. Nov 24, 2016 · Von Willebrand’s disease is subdivided into types 1, 2, and 3. 11 Type 1, which accounts for 70 to 80% of cases, is characterized by a quantitative deficiency of von Willebrand factor. Type 2 ...

  6. 280042-GPO_R1_v6. bleed a lot after a fairly minor cut; or are a woman who has very heavy or long menstrual periods, you should ask your doctor about an inherited bleeding disorder called von Willebrand disease (VWD). Named for Dr. Erik von Willebrand, a Finnish doctor who first described the condition in 1926, VWD affects your blood's ability ...

  7. Mar 2, 2024 · Von Willebrand disease (VWD) is a common bleeding disorder characterized by a deficiency or dysfunction of von Willebrand factor (VWF), a protein that plays a crucial role in blood clotting. Pregnancy can pose unique challenges for women with VWD, as there is an increased risk of bleeding complications during this time.

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