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Fixed-drug eruption (FDE) is an unusual and rare adverse drug reaction. This type of reaction is actually a delayed type of hypersensitivity reaction that occurs as lesions recurring at the same skin site due to repeated intake of an offending drug. Here is a case report of a 58-year-old male patient who developed intraoral FDEs after ingestion ...
Treatment of Drug Eruptions and Reactions. Discontinuation of offending drug. Sometimes antihistamines and corticosteroids. Most drug reactions resolve when drugs are stopped and require no further therapy. Whenever possible, chemically unrelated compounds should be substituted for suspect drugs.
May 23, 2022 · INTRODUCTION. Fixed drug eruption (FDE) is a distinctive type of cutaneous drug reaction that characteristically recurs in the same locations upon re-exposure to the offending drug. Acute FDE usually presents with a single or a small number of dusky red or violaceous plaques that resolve leaving postinflammatory hyperpigmentation ( picture 1A-C ).
Nov 9, 2022 · Fixed drug eruptions are seen in 2 % to 5 % of hospitalized patients and 1 % of outpatients. Fixed drug eruptions are rarer than exanthematous (morbilliform) eruptions, where 95 % of a drug reaction to the skin is seen. Fixed drug eruptions occur in males and females of all age groups. 5 % to 22 % of children report fixed drug eruptions.
Jul 17, 2021 · Biological agents are emerging in the treatment of severe drug eruption, which may be the trend of the treatment of severe drug eruption in the future. The prevention of severe drug eruptions is also essential. The increasing number of studies on severe drug eruptions will be greatly beneficial and will guide the management of these patients.
Dec 8, 2022 · Generalized bullous fixed drug eruption: Extensive bullous fixed drug eruption: Fixed drug eruption: Generalized bullous fixed drug eruption: Fixed drug eruption: Treatment: Topical 0.25% desoximetasone cream: Ibuprofen and high-dose oral prednisone, bullae drainage followed by mupirocin and Vaseline for wound care: Not discussed in the article
Sep 24, 2022 · 1. INTRODUCTION. Fixed drug eruption (FDE) is diagnosed clinically by linking exposure to a drug with the occurrence of fixed exanthematous reactions. It is a relatively common form of cutaneous adverse drug reaction that has been associated with over 100 medications worldwide. 1 , 2 , 3 In Nigeria, sulphonamides, particularly sulfadoxine ...
