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Jul 23, 2012 · Introduction. Dengue is a febrile illness that can have a fatal outcome in severe cases. It is a caused by a flavivirus with four distinct serotypes (DV-1, DV-2, DV-3, and DV-4). 1 The virus is spread between humans by mosquito vectors of the Aedes genus, ie, Aedes aegypti and Aedes albopictus. 2 The exact pathophysiology of severe dengue infection (dengue hemorrhagic fever and dengue shock ...
Oct 5, 2021 · Dengue virus belongs to the class of RNA viruses and subclass of enveloped single-stranded positive-sense RNA virus. It causes dengue fever (DF), dengue hemorrhagic fever (DHF), or dengue shock syndrome (DSS), where DHF and DSS are life-threatening. Even though dengue is an age-old disease, it is still a mystery and continues to be a global threat.
Oct 5, 2021 · Dengue virus belongs to the class of RNA viruses and subclass of enveloped single-stranded positive-sense RNA virus. It causes dengue fever (DF), dengue hemorrhagic fever (DHF), or dengue shock syndrome (DSS), where DHF and DSS are life-threatening. Even though dengue is an age-old disease, it is still a mystery and continues to be a global threat.
Aug 26, 2023 · Dengue is an emerging, mosquito-borne viral disease of international public health concern. Dengue is endemic in more than 100 countries across the world. However, there are no clinically approved antivirals for its cure. Drug repurposing proves to be an efficient alternative to conventional drug discovery approaches in this regard, as approved drugs with an established safety profile are ...
Apr 12, 2012 · VOL. 366 NO. 15. Dengue is a self-limited, systemic viral infection transmitted between humans by mosquitoes. The rapidly expanding global footprint of dengue is a public health challenge with an ...
Oct 5, 2022 · Dengue (DENG-gey) fever is a mosquito-borne illness that occurs in tropical and subtropical areas of the world. Mild dengue fever causes a high fever and flu-like symptoms. The severe form of dengue fever, also called dengue hemorrhagic fever, can cause serious bleeding, a sudden drop in blood pressure (shock) and death.
Dynamic behavior of Dengue and Zika viruses NS1 protein reveals monomer-monomer interaction mechanisms and insights to rational drug design J Biomol Struct Dyn . 2020 Sep;38(14):4353-4363. doi: 10.1080/07391102.2019.1677504.
