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  1. Apr 2, 2024 · Acute promyelocytic leukemia (APL) is a rare blood cancer that once was a fatal illness. Now, healthcare providers consider APL a curable disease, thanks to an innovative combination of chemotherapy and non-chemotherapy drugs.

  2. Prompt diagnosis and treatment of acute promyelocytic leukemia (APL), the M3 subtype of acute myeloid leukemia (AML), is very important because people with APL can quickly develop life-threatening blood-clotting or bleeding problems if not treated.

  3. Acute promyelocytic leukemia (APML, APL) is a subtype of acute myeloid leukemia (AML), a cancer of the white blood cells. In APL, there is an abnormal accumulation of immature granulocytes called promyelocytes.

  4. Acute promyelocytic leukemia (APL) is an aggressive type of acute myeloid leukemia (AML). It happens when there are too many of the blood-forming cells called promyelocytes in the blood and bone marrow.

  5. May 24, 2023 · Acute promyelocytic leukemia (APL) is a type of acute myeloid leukemia (AML). With proper treatment, the survival rates are high. APL is a relatively rare cancer, accounting for about 7–8% of...

  6. Jun 26, 2023 · Introduction. Acute promyelocytic leukemia is a distinguished subset of acute myeloid leukemia which is characterized by fusion gene transcript PML-RAR-alpha and high cure rates with treatment.

  7. Aug 5, 2021 · APL is a subtype of an acute form of leukemia called acute myeloid leukemia (AML). It’s one of the eight subdivisions of AML and is characterized by an increase in immature white blood cells...

  8. Acute promyelocytic leukemia (APL) is a rare cancer affecting the blood and bone marrow. It occurs primarily in middle-aged adults, but it also can affect children. Prompt diagnosis and treatment reduce symptoms long-term (remission) and often cure APL.

  9. Acute promyelocytic leukemia (APL) is a unique subtype of acute myeloid leukemia (AML). APL cells have a very specific abnormality that involves chromosomes 15 and 17, leading to the formation of an abnormal fusion gene called PML/RARα. This mutated gene causes many of the features of the disease.

  10. Acute promyelocytic leukemia (APL) is treated differently than other forms of acute myeloid leukemia. Many people with APL are first treated with a drug called all-trans-retinoic acid (ATRA), also called tretinoin (Vesanoid®).

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