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Structures of ebola virus proteins are giving new hope for fighting this deadly virus. Cross section through ebola virus shows proteins in blue, green and magenta, the RNA genome in yellow, and the membrane in light purple. Atomic structures are shown on the right, with portions that have not been determined shown with schematic circles.
Apr 14, 2016 · The database is also interfaced with the Jmol plugin to visualize three-dimensional structure of Ebolavirus proteins . This feature helps the users to analyze the functionally active proteins associated with Ebolavirus pathogenicity. The Ebola virus belongs to Zaire ebolavirus species and Zaire ebolavirus infections have case fatality rate of ...
May 6, 2020 · Published May 6, 2020. N Engl J Med 2020;382: 1832 - 1842. DOI: 10.1056/NEJMra1901594. VOL. 382 NO. 19. Ebola virus (EBOV) was the best-known and most extensively studied member of the Filoviridae ...
Sep 28, 2022 · Filovirus has a large polymerase (L) protein and the cofactor viral protein 35 (VP35), which constitute the basic functional unit responsible for virus genome RNA synthesis 3. Owing to its ...
Sep 1, 2014 · The structure of the C-terminal domain of the Zaire ebolavirus nucleoprotein (NP), encompassing residues 641–739, was determined in two distinct crystal forms. The domain has a novel fold that is distantly related to the β-grasp fold. Keywords: viral protein, Ebolavirus, nucleoprotein.
Apr 9, 2019 · Ebola virus, formally called Zaire ebolavirus, is a rare virus that infects humans and nonhuman animals such as pigs and other primates. It is one among several viruses within the genus Ebolavirus ...
Oct 17, 2018 · First, a previously reported crystal structure of Ebola NP residues 38−385 (PDB: 4YPI) 8 served as the initial model and was docked as a rigid body into our 3.6 Å-resolution cryo-EM map. Next ...
