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Nov 16, 2021 · F or more detail on this group refer to the chapter Photodermatoses: drug / chemical-induced ; A fixed drug eruption: the rash comes and goes on exposure to the drug, the same body site is affected every time. The lesion(s) is a well-demarcated erythematous plaque that may blister, tending to heal with post-inflammatory hyperpigmentation
Fixed drug eruption (single or multiple recurring blistered plaques) Lichenoid drug eruption (lichen planus-like reaction) Drug-induced photosensitivity: phototoxicity (exaggerated sunburn) or photoallergy (eczema in sun-exposed sites) Bullous drug eruptions (immunobullous disease is important to recognise, as drug withdrawal leads to clearance)
Aug 8, 2022 · Although patch testing was negative, an oral rechallenge with 100 mg doxycycline was positive. Fixed drug eruptions are common, 1, 2 and constitute 14%–22% of cutaneous drug reactions among children. 3 They are type IV hypersensitivity reactions that appear within 1 week after initial drug exposure, but may occur within minutes upon re ...
Apr 8, 2016 · A fixed-drug eruption (FDE) is a reaction characterized by cutaneous lesions that appear due to exposure to a particular drug. Barbiturates, carbamazepine, sulfamethoxazole, and tetracyclines have all been associated with causation of FDEs. Although these drugs are more commonly associated with FDEs, any introduction of a medication has the ...
Different skin reactions following ingestion of ibuprofen have been introduced up to now. Contact dermatitis, photosensitivity, angioedema, and urticarial rashes are some of the described mucocutaneous side effects associated with ibuprofen. [ 6] However, bullous fixed drug eruption (FDE) due to ibuprofen ingestion is an uncommon skin reaction.
A fixed-drug eruption (FDE) is an immunological cutaneous adverse reaction characterized by sharply defined lichenoid lesion/s which occur/s at the same location every time there is exposure to the causative substance. Exogenous agents are the only known cause of FDE. It does not occur spontaneously or following an infection.
