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  1. 2 hours ago · Abstract. Diabetes mellitus is a well-established risk factor for the development of peripheral arterial disease (PAD). The spectrum of disease in PAD ranges from asymptomatic to rest pain and tissue loss. Patients with diabetes frequently are asymptomatic until they develop a foot wound and subsequently experience poor wound healing due to the ...

  2. 2 hours ago · In the patient with diabetes, peripheral neuropathy may develop in isolation or commonly in parallel with atherosclerotic peripheral vascular disease. The latter involves major in-flow vessels to the lower extremity but commonly is associated with occlusive lesions of the tibial and peroneal arteries between the knee and ankle.

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