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1 day ago · Claude of France (13 October 1499 – 26 July 1524) reigned as Duchess of Brittany from 1514 until her death in 1524 and was Queen of France from 1515 to 1524 as the wife of King Francis I. She was the eldest daughter of King Louis XII of France and Duchess Anne of Brittany. She is known for having likely been a queen with Down syndrome.
