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10 hours ago · The most common indications for antibiotic prescription were sepsis in neonates and central nervous system infection in older children. The documentation of reason in notes increased from 33 to 100%, while the stop-review date also increased from 19.4 to 70%.
10 hours ago · Sepsis shock was evaluated by clinician according to the Sepsis-3 12. Assessment II (APACHE II) score is used to calculate the severity of the disease within 24 h followingthe onset of BSI.
10 hours ago · In addition, 23 (32%) of the newborns in the P-PROM group were admitted to the neonatal intensive care unit (NICU), 3 (13%) developed sepsis, 8 (11%) required ventilatory support, and Apgar scores of 5 and 6 per minute were observed in 23 (33%) of the cases and 13 (56%) remained in NICU for 3 to 5 days (p < 0.05) (Table 1).
10 hours ago · Chronic lung disease (CLD) of prematurity, a common cause of morbidity and mortality in preterm-born infants, has a multifactorial aetiology. This review summarizes the current evidence for the effect of the gut and airway microbiota on the development of CLD, highlighting the differences in the early colonisation patterns in preterm-born infants compared to term-born infants. Stool samples ...
10 hours ago · There is little published evidence on the impact of epigenetics on diverticulosis or diverticulitis but there have been interesting studies demonstrating immune cell epigenetic-mediated susceptibility to sepsis 107. Early epigenetic data suggest variation in gene expression within molecular pathways in early- and late-onset diverticulitis, with ...
10 hours ago · The onset of mitochondrial epilepsy due to nDNA mutations is early and seizures are the most common initial symptom. DEE is the most common phenotype. Characteristic MRI abnormalities in the brain may be helpful in the diagnosis of primary mitochondrial disease. People with MDS typically face challenges in seizure control and have a poor prognosis.
10 hours ago · Background The aim of this retrospective cohort study was to develop and validate on multiple international datasets a real-time machine learning model able to accurately predict persistent acute kidney injury (AKI) in the intensive care unit (ICU). Methods We selected adult patients admitted to ICU classified as AKI stage 2 or 3 as defined by the “Kidney Disease: Improving Global Outcomes ...
