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1 day ago · Santa Fe (/ ˌ s æ n t ə ˈ f eɪ, ˈ s æ n t ə f eɪ / SAN-tə FAY, - fay; Spanish:) is the capital of the U.S. state of New Mexico.With a population of 87,505 at the 2020 census, it is the fourth-most populous city in the state.