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13 hours ago · The intravenous dose causing 50% of opioid-naive experimental subjects to die (LD 50) is "3 mg/kg in rats, 1 mg/kg in cats, 14 mg/kg in dogs, and 0.03 mg/kg in monkeys." [94] The LD 50 in mice has been given as 6.9 mg/kg by intravenous administration, 17.5 mg/kg intraperitoneally, 27.8 mg/kg by oral administration. [95]
- Paul Janssen
Further reading. Lewi, Paul J., Successful Pharmaceutical...
- Analgesic
An analgesic drug, also called simply an analgesic,...
- Opioid
Opioids are a class of drugs that derive from, or mimic,...
- Controlled Substance Act
Controlled Substances; Long title: An Act to amend the...
- Paul Janssen
13 hours ago · The sun protection factor (SPF rating, introduced in 1974) is a measure of the fraction of sunburn-producing UV rays that reach the skin. For example, "SPF 15" means that 1 ⁄ 15 of the burning radiation will reach the skin, assuming sunscreen is applied evenly at a thick dosage of 2 milligrams per square centimeter (mg/cm 2). It is important ...
13 hours ago · Cell culture or tissue culture is the process by which cells are grown under controlled conditions, generally outside of their natural environment. After cells of interest have been isolated from living tissue, they can subsequently be maintained under carefully controlled conditions.
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- 37 °C
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