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Caroline Schlüter currently works at the Biopsychology, Ruhr-Universität Bochum. Caroline does research in Biological Psychology and Personality Neuroscience.
Research fellow, Ruhr-University Bochum, Germany - Cited by 684
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- Introduction
- Methods
- Results
- Discussion
- Funding
- Author Contributions
- Acknowledgments
‘Never put off until tomorrow what you can do today.’ Although we are probably all familiar with sayings like this, it can be difficult to actually stick to them. Especially when we are facing a demanding task, we happen to first rush into other, simpler activities, before we devote ourselves to the actual problem. This phenomenon is commonly known...
Participants
We present results from a cohort of 278 neurologically and psychologically healthy subjects with a mean age of 24.05 (s.d. = 3.87) years (range, 18–37 years), including 143 males (mean age, 24.53 years; s.d. = 4.11 years) and 135 females (mean age, 23.54 years; s.d. = 3.54 years). A total of 99 out of the 135 participating women used hormonal contraceptives. The sample mainly comprised university students of different majors (mean years of education, 16.44 years; s.d. = 2.61 years), who recei...
Genotyping
The analyzed SNP rs10770141 (C-824T) in the TH promoter region was selected due to its potential functional impact on the transcriptional activity, implying that the T-allele carriers may have higher TH activities and retain higher levels of catecholamines in the brain (Horiguchi et al., 2014). Genotyping was performed by : PCR-Restriction Fragment Length Polymorphism (PCR-RFLP) techniques. Primers were designed with Primer Express 2.0 software (Applied Biosystems). All other details of the m...
Imaging
Since our previous study indicated that interindividual differences in AOD are associated with interindividual differences in morphology and functional connectivity of the amygdala (Schlüter et al., 2018a), we aim to investigate whether the neural correlates of AOD are mediated by THgene expression. The acquisition and analysis of imaging data are described in more detail below.
Genotyping revealed 113 homozygous CC genotypes, 101 heterozygous CT genotypes and 62 homozygous TT genotypes. For two participants, the TH genotype could not be determined. The final sample was thus N = 276. For further statistical analysis, we combined the heterozygous genotype with the rare homozygous TT genotypes to ensure greater statistical p...
In the current study, we examined whether different genotypes of the functional TH promoter polymorphism rs10770141 (C-824T) are associated with interindividual differences in the tendency to procrastinate, as measured by Kuhl’s (1994a) AOD scale. Here we could show that there was a significant interaction between TH genotype and sex. While in wome...
This work was supported by the Deutsche Forschungsgemeinschaft (grant numbers GU 227/16-1 and GE 2777/2-1), SFB 940 project B08 and SFB 1280 project A03 (project number 316803389), as well as the Mercur Foundation (grant number An-2015-0044).
E.G. conceived the project and supervised the experiments. C.S., L.A., M.P., O.G., C.B., S.O. and E.G. designed the project. L.A. planned and performed genetic experiments. C.S., C.F. and P.F. collected data. C.S., L.A., C.F., C.B, S.O. and E.G. analyzed the data. C.S., C.B. and E.G. wrote the paper. All authors discussed the results and edited the...
The authors thank all research assistants for their support during the behavioral measurements. Furthermore, the authors thank PHILIPS Germany (Burkhard Mädler) for the scientific support with the MRI measurements and Tobias Otto for technical assistance.
- Caroline Schlüter, Larissa Arning, Christoph Fraenz, Patrick Friedrich, Marlies Pinnow, Onur Güntürk...
- 2019
Aug 17, 2018 · Our results demonstrate a significant negative correlation between decision-related action orientation (AOD) and amygdala volume. Further, we showed that the functional resting-state connectivity between the amygdala and the dorsal anterior cingulate cortex was significantly associated with AOD.
- Caroline Schlüter, Christoph Fraenz, Marlies Pinnow, Patrick Friedrich, Onur Güntürkün, Erhan Genç
- 2018
Aug 22, 2018 · The research team headed by Caroline Schlüter, Dr. Marlies Pinnow, Professor Onur Güntürkün, and Dr. Erhan Genç from the Department of Biopsychology published the results in the journal...
Caroline Schlüter 1 , Christoph Fraenz 1 , Marlies Pinnow 1 , Patrick Friedrich 1 , Onur Güntürkün 1 , Erhan Genç 1. Affiliation. 1 Biopsychology, Faculty of Psychology, Ruhr University Bochum. PMID: 30118388. DOI: 10.1177/0956797618779380. Abstract. Individuals differ in their ability to initiate self- and emotional-control mechanisms.
