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1. www.mayoclinic.org › diseases-conditionsAmyotrophic lateral sclerosis (ALS) - Symptoms and causes

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   Apr 10, 2024 · ALS is a fatal nervous system disease that affects nerve cells in the brain and spinal cord, causing muscle weakness and loss of control. Learn about the symptoms, causes, diagnosis and treatment options for ALS, also known as Lou Gehrig's disease, from Mayo Clinic experts.

2. People also ask

   What is a defining feature of ALS?

   • The defining feature of ALS is the death of both upper motor neurons (located in the motor cortex of the brain) and lower motor neurons (located in the brainstem and spinal cord). In ALS with frontotemporal dementia, neurons throughout the frontal and temporal lobes of the brain die as well.

   ALS - Wikipedia

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   Is ALS a sporadic disease?

   • Nearly all cases of ALS are considered sporadic, meaning the disease seems to occur at random with no clearly associated risk factors and no family history of the disease. Although family members of people with ALS are at an increased risk for the disease, the overall risk is very low, and most will not develop ALS.

   Amyotrophic Lateral Sclerosis (ALS) | National Institute of

   www.ninds.nih.gov/health-information/disorders/amyotrophic-lateral-sclerosis-als

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   What does ALS stand for?

   • "Amyotrophic lateral sclerosis" (PDF). Nature Reviews. Disease Primers. 3 (17071): 17071. doi: 10.1038/nrdp.2017.71. PMID 28980624. S2CID 1002680. Archived (PDF) from the original on 1 December 2020. Retrieved 20 December 2019. ^ "Understanding ALS". The ALS Association. Archived from the original on 26 October 2020. Retrieved 28 October 2020.

   ALS - Wikipedia

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3. www.als.org › understanding-als › what-is-alsWhat is ALS? - Amyotrophic Lateral Sclerosis | The ALS ...

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   ALS is a fatal neurodegenerative disease that affects nerve cells in the brain and spinal cord, leading to muscle weakness and paralysis. Learn about the types, causes, symptoms, diagnosis, and treatments of ALS, and how to access support and resources from The ALS Association.

4. en.wikipedia.org › wiki › ALSALS - Wikipedia

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   Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) or Lou Gehrig's disease in the United States, is a rare but terminal neurodegenerative disorder that results in the progressive loss of both upper and lower motor neurons that normally control voluntary muscle contraction.

5. Top Stories

   • 
     New Atlas

     ALS breakthrough: Synapse-regenerating pill moves to phase 2 human trials

     A pioneering once-a-day pill that regenerates nerve cell connections damaged by ALS has been FDA-approved for ongoing clinical trials. The drug is now being given to those with ALS and could be a watershed moment in the treatment of the fatal disease.

     3 hours ago

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     FierceBiotech

     Public-private collaboration aims to take ALS therapies beyond ‘a shot in the dark’

     11 hours ago

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     MovieMaker on MSN.com

     Brian Wallach Got an ALS Diagnosis of 6 Months to Live - 7 Years Ago. No Ordinary Campaign Chronicles His Victories Since

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     NBC 10 Philadelphia on MSN.com

     Ferko String Band surprises fellow long-time Mummer who is currently fighting ALS

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   • CBS News on MSN.com

     Colorado group empowers ALS patients with special ski session: "The feeling brings me peace"

     6 days ago

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6. www.hopkinsmedicine.org › health › conditions-andAmyotrophic Lateral Sclerosis (ALS) | Johns Hopkins Medicine

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   ALS is a fatal disease that affects nerve cells in the spinal cord and brain, causing muscle weakness and paralysis. Learn about the types, causes, symptoms, diagnosis, treatment, and research of ALS from Johns Hopkins experts.

7. www.als.org › understanding-alsHelping You Understand ALS | The ALS Association

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   May 17, 2024 · ALS is a fatal disease that causes progressive muscle weakness and paralysis. Learn about the symptoms, diagnosis, causes, and treatment of ALS from the leading ALS organization in the U.S.

8. www.ninds.nih.gov › health-information › disordersAmyotrophic Lateral Sclerosis (ALS) | National Institute of ...

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   Apr 10, 2024 · ALS is a neurological disorder that affects motor neurons and causes muscle weakness, twitching, and atrophy. Learn about the risk factors, diagnosis, and treatment options for this progressive and fatal disease from the National Institute of Neurological Disorders and Stroke.

9. my.clevelandclinic.org › health › diseasesAmyotrophic Lateral Sclerosis (ALS) - Cleveland Clinic

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   Jun 15, 2021 · ALS is a neuromuscular disorder that causes muscle weakness and atrophy. Learn about the types, risk factors, diagnosis and management of ALS, also known as Lou Gehrig’s disease.