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  1. www.nasa.gov › humans-in-space › twins-studyTwins Study - NASA

    Sep 20, 2023 · The landmark Twins Study brought ten research teams around the country together to observe what physiological, molecular, and cognitive changes could happen to a human from exposure to spaceflight.

    • About

      A study new to NASA took place throughout the historical...

    • A Question of Aging
    • Gene Expression in Space
    • Spaceflight’s Influence on The Mind
    • The Space Explorer’s Body

    One of the ten teams, led by Susan Bailey, a professor of radiation and cancer biology at Colorado State University, focused on telomeres, the “caps” that protect the ends of DNA strands. On Earth, these telomeres get depleted over the course of a person’s lifetime as each round of DNA replication wears away at them. When Bailey’s team analyzed the...

    Researchers also studied Scott’s genome to see if gene expression changed during flight, as it tends to do in stressful situations. A team led by Chris Mason, a geneticist at Weill Cornell Medicine, studied DNA and RNA modifications that would signal epigenetic adaptation. They observed some changes in how genes were expressed, and these variations...

    In one potentially concerning result, a team studying cognition found that Scott’s performance on a series of cognitive tests declined in the post-flight period. Mathias Basner, a psychiatry professor at the University of Pennsylvania, and his team designed a specialized cognitive test battery for NASA—a series of 10 computerized tasks to measure d...

    Throughout the rest of Scott’s body, researchers observed other changes related to spaceflight. In a study of the microbiome, the community of bacteria living in the human gut, a team led by researchers from Northwestern University found that the proportions of different types of bacteria changed during Scott’s year in space. Overall diversity of t...

  2. Apr 11, 2019 · Results are finally published on NASA's Twins Study, which followed astronauts Scott and Mark Kelly as Scott spent nearly a year on the International Space Station.

    • 2 min
    • Sarah Lewin
  3. NASA will track how identical twins Mark and Scott Kelly change as one brother heads into orbit for a record-long year mission. When Scott Kelly calls home from the International Space Station...

  4. Apr 11, 2019 · TWINS APART Astronaut Scott Kelly (left) spent a year in space on the International Space Station while his identical twin brother, astronaut Mark Kelly (right), remained on Earth. They were...

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