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Erwin Chargaff (11 August 1905 – 20 June 2002) was an Austro-Hungarian-born American biochemist, writer, Bucovinian Jew who emigrated to the United States during the Nazi era, and professor of biochemistry at Columbia University medical school. He wrote a well-reviewed autobiography, Heraclitean Fire: Sketches from a Life Before Nature.
World Scientific, 2016. Lived 1905 – 2002. Erwin Chargaff's research paved the way for the discoveries of DNA's structure and its method of replication. His observation that DNA varies from species to species made it highly credible that DNA was genetic material.
His two main discoveries, (i) that in any double-stranded DNA the number of guanine units equals thenumber of cytosine units and the number of adenine units equals the number ofthymine units and (ii) that the composition of DNA varies from one species toanother, are now known as Chargaff's Rules.
- Nicole Kresge, Robert D. Simoni, Robert L. Hill
- 2005
Jun 20, 2002 · The American biochemist Erwin Chargaff (born 1905) discovered that DNA is the primary constituent of the gene, thereby helping to create a new approach to the study of the biology of heredity. Erwin Chargaff was born in Austria on August 11, 1905.
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One other key piece of information related to the structure of DNA came from Austrian biochemist Erwin Chargaff. Chargaff analyzed the DNA of different species, determining its composition of A, T, C, and G bases. He made several key observations: A, T, C, and G were not found in equal quantities (as some models at the time would have predicted)
- What is a codon and how does it relate to a DNA function and structure ?A codon is the name for a group of three subsequent nucleotides in RNA. Since RNA is transcribed from DNA, the DNA sequence will determine the sequ...
- well I have 2 doubts: 1) in the second para under the topic 'right hand helix' i couldn't understand...As far as the 2nd question is concerned , it is because the double helix should have a uniform diameter all throughout otherwise there might be pro...
- Am I understanding this correctly? The amount of the total bases in a cell's DNA is always the same ...Not exactly. The amount of each type of base in a cell's DNA is the _same in all cells in the whole organism_. Genetic code is the same, but gene e...
- I want to make sure I have these ideas true! It may have nothing to do with the article but I found ...Seems mostly correct. The one mistake I notice is that I think the word you were looking for was histones (not histamin). Chromatin is composed of...
- Why is adenine a purine base?I'm not sure it is the NH2 group which accepts protons most readily to make it a base. I think it could be the nitrogens in the rings, which I thin...
- How can you tell the helix is right handed?You can tell if if the helix is right handed or left handed based on the way it twists. Here's a link to an image that shows the difference between...
- What is the difference between DNA and RNAI will answer you the way I have answered this question before with other users. I hope it is adequate. There are several differences. To start, DN...
- What are the four different kinds of nitrogen bases?The four nitrogenous bases are as follows: Adenine, Thymine, Guanine, and Cytosine. Cytosine and Thymine are pyrimidines Adenine and Guanine are pu...
- What is the order of the nitrogenous bases of the DNA if I have to put up a 3d model?There isn't a single order — all combinations along a strand are possible. The only thing that is fixed in DNA is that A pairs with T, and G pairs...
genetics research. In heredity: Structure and composition of DNA. …it was found by biochemist Erwin Chargaff that the amount of A is always equal to T, and the amount of G is always equal to C. Read More. Other articles where Erwin Chargaff is discussed: heredity: Structure and composition of DNA: …it was found by biochemist Erwin Chargaff ...
Health & Medicine. Affiliations. Columbia University. Erwin Chargaff was awarded the National Medal of Science for fundamental chemical and biological studies establishing the basis for modern concepts of the mechanisms of protein synthesis and the genetic role of nucleic acids.
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