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James Edward Rothman (born November 3, 1950) is an American biochemist. He is the Fergus F. Wallace Professor of Biomedical Sciences at Yale University, the Chairman of the Department of Cell Biology at Yale School of Medicine, and the Director of the Nanobiology Institute at the Yale West Campus. [2] Rothman also concurrently serves as adjunct ...
- United States
- Harvey Lodish
- American
- Cell biology
James Rothman is a distinguished biochemist and cell biologist who discovered the molecular machinery of membrane fusion and vesicle trafficking. He is the Sterling Professor of Cell Biology, the Director of Nanobiology Institute, and the recipient of the Nobel Prize in Physiology or Medicine (2013).
- (203) 737-5293
- james.rothman@yale.edu
James Rothman was born in Haverhill, Massachusetts in the United States. He studied at Yale University in New Haven, Connecticut, and later received his Ph.D. from Harvard University in Cambridge, Massachusetts, in 1976.
- Childhood
- Yale
- Harvard
- Deep and Enduring Scientific Friendships
- Observations on Style from A Life in Science
- Additional Personal History
- Curriculum Vitae
From the earliest time I can remember I wanted to be a scientist, especially a physicist. I am not entirely sure where this came from, but at least in part it must have come from my parents (Fig. 1) who deeply valued education, especially in science and medicine. I was really fortunate and owe my parents a lot – they made me feel that I could do an...
Yale provided the perfect environment in which a committed young scientist could develop while also immersed in the broader culture. Yale was big enough to provide every opportunity, yet organized into relatively intimate units (Colleges) small enough to foster the individual. The students had all varieties of interests, and my friends were drawn l...
My father had cnvinced me that I should go to a medical school rather than directly to a PhD program. At that point my knowledge of biology was as narrow as my knowledge of physics was deep, and it would have been impossible to make an informed choice of which discipline in biology to focus on. Therefore, I entered Harvard Medical School (in 1971) ...
A life in research provides many opportunities to meet remarkable people as a student and afterwards around the world. It is hard to over-emphasize the importance of several formative, warm and enduring friendships for my development and success as a scientist. Some evolved from what we would today call mentoring relationships, initially with somew...
As a closing bookend, I will offer some observations that may be of interest to others, especially younger scientists. This is not necessarily to impart specific advice, which would be disingenuous as I rarely followed the advice I was given as a young man; it is more to offer the use of some of my personal experiences as a springboard for generali...
In addition to me (1950) my parents Gloria Rothman (née Hartnick, born 1923) and Martin Rothman (1915–2005) had two children, Richard (1953) and John (1955). My brother Richard is an MD-PhD who recently retired from the NIH after many years as a leading researcher in neuropharmacology, and is now in practice in Psychiatry. John is a successful atto...
James Edward Rothman was born on November 3, 1950 in Haverhill, Massachusetts (U.S.A.). He went to public schools in Haverhill, Massachusetts for elementary school through 8th grade, and then to Pomfret School (Pomfret, Connecticut) in 1964, from which he graduated in 1967. He then matriculated at Yale College, graduating summa cum laude in 1971 wi...
May 8, 2024 · James E. Rothman (born November 3, 1950, Haverhill, Massachusetts, U.S.) is an American biochemist and cell biologist who discovered the molecular machinery involved in vesicle budding and membrane fusion in cells. Cellular vesicles, which are bubblelike structures, play a critical role in the storage and transport of molecules within cells ...
- Kara Rogers
Oct 14, 2013 · James Rothman won the 2013 Nobel Prize in Physiology or Medicine for his discoveries of vesicle traffic in cells. He conducted much of his research at Memorial Sloan Kettering, where he also developed a protein complex to trigger the immune system to attack cancer cells.
Oct 7, 2013 · James Rothman, a Yale professor and alumnus, was honored for his research on how cells communicate with each other and with the environment. He pioneered the use of cell-free systems to study the molecular mechanisms of vesicle trafficking and exocytosis.
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