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- Season 5 overviewSep 22, 2011-May 10, 201224 episodesSeason 5 episodes1. The Skank Reflex Analysis Sep 22, 2011
- Penny worries that she has ruined her relationship with her friends.
- 2. The Infestation Hypothesis Sep 22, 2011
- Amy is caught in the middle when Penny and Sheldon argue over a pre-owned chair.
- 3. The Pulled Groin Extrapolation Sep 29, 2011
- Bernadette, Howard and Mrs. Wolowitz spend the weekend together.
- 4. The Wiggly Finger Catalyst Oct 6, 2011
- Raj wants a girlfriend, so Penny introduces him to a woman he can communicate with.
- 5. The Russian Rocket Reaction Oct 13, 2011
- Wil Wheaton invites Leonard and Sheldon to a party at his house; Howard receives an opportunity.
- 6. The Rhinitis Revelation Oct 20, 2011
- Sheldon finds himself competing with the gang for his mother's attention when she visits.
- 7. The Good Guy Fluctuation Oct 27, 2011
- An attractive comic book artist tests Leonard and Priya's relationship.
- 8. The Isolation Permutation Nov 3, 2011
- Amy is devastated when Penny and Bernadette shop for wedding dresses without her.
- 9. The Ornithophobia Diffusion Nov 10, 2011
- Leonard and Penny spend time alone; Sheldon tries to face his fear of birds.
- 10. The Flaming Spittoon Acquisition Nov 17, 2011
- Sheldon is jealous when Stuart, from the comic book store, asks Amy out on a date.
- 11. The Speckerman Recurrence Dec 8, 2011
- Leonard must face the bully who targeted him in high school; Penny confronts her past actions.
- 12. The Shiny Trinket Maneuver Jan 12, 2012
- Amy is upset with Sheldon when he isn't impressed with her recent accomplishment.
- 13. The Recombination Hypothesis Jan 19, 2012
- Everything could change when Leonard spontaneously invites Penny to a romantic dinner.
- 14. The Beta Test Initiation Jan 26, 2012
- Penny and Leonard experiment with their new relationship; Raj forms an unusual bond.
- 15. The Friendship Contraction Feb 2, 2012
- Leonard starts to reconsider his friendship with Sheldon; Wolowitz tries to choose a nickname.
- 16. The Vacation Solution Feb 9, 2012
- Sheldon goes to work with Amy in her lab when the university forces him to take a vacation.
- 17. The Rothman Disintegration Feb 16, 2012
- Sheldon and Kripke compete for a corner office; Penny receives a gift from Amy.
- 18. The Werewolf Transformation Feb 23, 2012
- Sheldon's routine is turned upside down when his barber gets sick.
- 19. The Weekend Vortex Mar 8, 2012
- Sheldon decides to play video games with the guys instead of attending a party with Amy.
- 20. The Transporter Malfunction Mar 29, 2012
- After receiving new "Star Trek" collectibles, Sheldon finds himself haunted by Mr. Spock.
- 21. The Hawking Excitation Apr 5, 2012
- When Wolowitz works with Stephen Hawking, Sheldon is determined to meet the famous scientist.
- 22. The Stag Convergence Apr 26, 2012
- Knowledge of Howard's sexual history makes Bernadette reconsider their future together.
- 23. The Launch Acceleration May 3, 2012
- Wedding plans are jeopardized when NASA reschedules Howard's mission; Leonard surprises Penny.
- 24. The Countdown Reflection May 10, 2012
- The gang tries to help Wolowitz and Bernadette get married before the space launch.