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- Season 2 overviewSep 25, 2005-May 15, 200627 episodesSeason 2 episodes27. Losing My Religion May 15, 2006
- Pressure to find a new heart for Denny increases; Callie confronts George.
- Pressure to find a new heart for Denny increases; Callie confronts George.
- 25. 17 Seconds May 14, 2006
- Finn offers a health update on Doc; Meredith must work with Callie.
- 24. Damage Case May 7, 2006
- The interns care for a family in a car accident; Burke and Izzie have a suggestion for Denny.
- 23. Blues for Sister Someone Apr 30, 2006
- Izzie grills George about the details of his life while Burke treats his musical hero.
- 22. The Name of the Game Apr 2, 2006
- George begins to overstay his welcome; Meredith learns a secret.
- 21. Superstition Mar 19, 2006
- Uncanny events at the hospital bring out the doctors' superstitious sides.
- 20. Band-Aid Covers the Bullet Hole Mar 12, 2006
- It becomes a bad day for Christina when Bailey instructs her to take care of her baby.
- 19. What Have I Done to Deserve This? Feb 26, 2006
- Meredith and George suddenly find themselves at odds at work.
- 18. Yesterday Feb 19, 2006
- Someone from Derek and Addison's past arrives in Seattle; Burke learns Christina's secret.
- 17. As We Know It Feb 5, 2006
- Despite the best efforts of the Seattle Grace staff, the code-black situation escalates.
- 16. It's the End of the World Feb 5, 2006
- Meredith has a premonition of a bad day; a medical case threatens the lives of everyone in the OR.
- 15. Break on Through Jan 29, 2006
- Nurses go on strike, leaving the doctors to fend for themselves.
- 14. Tell Me Sweet Little Lies Jan 22, 2006
- Meredith and Cristina lie to each other about their relationships.
- 13. Begin the Begin Jan 15, 2006
- Izzie finds chemistry with a patient awaiting a heart transplant.
- 12. Grandma Got Run Over by a Reindeer Dec 11, 2005
- Burke and Yang disagree on how to treat a child who does not seem to want a needed heart-transplant.
- 11. Owner of a Lonely Heart Dec 4, 2005
- An inmate jeopardizes her health to get out of solitary confinement.
- 10. Much Too Much Nov 27, 2005
- Meredith's one-night stand comes to the hospital for treatment.
- 9. Thanks for the Memories Nov 20, 2005
- The holiday is more difficult for the interns and residents than any of them is willing to admit.
- 8. Let It Be Nov 13, 2005
- Derek and Addison's close friends come to Seattle Grace seeking radical surgery.
- 7. Something to Talk About Nov 6, 2005
- A male patient who seems to have a hysterical pregnancy fascinates the staff.
- 6. Into You Like a Train Oct 30, 2005
- A train crash brings several seriously injured patients to the hospital.
- 5. Bring the Pain Oct 23, 2005
- A young woman's traditionalist, religious father forbids her to have a life-saving operation.
- 4. Deny, Deny, Deny Oct 16, 2005
- Cristina proves to be a difficult patient; Meredith's mother keeps the staff running in circles.
- 3. Make Me Lose Control Oct 9, 2005
- Family secrets become public when Meredith's mother is brought to Seattle Grace for surgery.
- 2. Enough Is Enough (No More Tears) Oct 2, 2005
- A family arrives at Seattle Grace Hospital after a serious car accident.
- 1. Raindrops Keep Falling on My Head Sep 25, 2005
- Meredith and Cristina discuss their relationship woes at a bar; the bartender collapses.
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