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- Season 12 overviewSep 24, 2015-May 19, 201624 episodesSeason 12 episodes24. Family Affair May 19, 2016
- Meredith and Maggie offer Amelia support; Jo admits she's been keeping things from Alex.
- 23. At Last May 12, 2016
- Amelia and Owen deepen their relationship; Alex has a clearer view of his future with Jo.
- 22. Mama Tried May 5, 2016
- Alex and April assist a pregnant teen going through a medical crisis; Callie and Arizona butt heads.
- 21. You're Gonna Need Someone on Your Side Apr 28, 2016
- Stephanie has difficulty with boundaries; Callie and Arizona turn to their friends for support.
- 20. Trigger Happy Apr 21, 2016
- Callie tries to make a decision about Sophia's future without consulting Arizona.
- 19. It's Alright, Ma (I'm Only Bleeding) Apr 14, 2016
- Miranda forms an advisory committee to recommend disciplinary action against Ben.
- 18. There's a Fine, Fine Line Apr 14, 2016
- Ben operates on a pregnant mother even though he does not have the proper surgical equipment.
- 17. I Wear the Face Apr 7, 2016
- Meredith goes on a ride to pick up a heart for a transplant; a musician who has MS is admitted.
- 16. When It Hurts So Bad Mar 31, 2016
- Meredith regrets taking a step forward with Will; Maggie feels disconnected.
- 15. I Am Not Waiting Anymore Mar 24, 2016
- Jackson finds out about April's pregnancy; Alex and the doctors tackle an organ transplant surgery.
- 14. Odd Man Out Mar 17, 2016
- Turmoil ensues when staff pairings are changed; Arizona takes a risk helping a pregnant woman.
- 13. All Eyez on Me Mar 10, 2016
- Meredith, Bailey, Jackson, Callie and Jo travel to a military hospital to perform a risky surgery.
- 12. My Next Life Mar 3, 2016
- A patient from Meredith's first surgery is re-admitted to the hospital with an aneurysm.
- 11. Unbreak My Heart Feb 24, 2016
- Flashbacks reveal the evolution of April and Jackson's relationship.
- 10. All I Want Is You Feb 18, 2016
- As everyone deals with Meredith's trauma, Maggie and Callie perform a risky surgery on a teenager.
- 9. The Sound of Silence Feb 11, 2016
- A patient attacks Meredith; after Penny learns what happened, the doctors rush to save Meredith.
- 8. Things We Lost in the Fire Nov 19, 2015
- As gossip continues to spread, a wildfire sends many firefighters to the hospital.
- 7. Something Against You Nov 12, 2015
- Bailey urges Ben to ask their roommate to leave; Arizona wants to start dating again.
- 6. The Me Nobody Knows Nov 5, 2015
- A new resident transfers to Grey Sloan Memorial; a young boy from the Middle East needs treatment.
- 5. Guess Who's Coming to Dinner Oct 22, 2015
- Maggie ditches cooking duties at her sister's dinner party to rush to the hospital.
- 4. Old Time Rock and Roll Oct 15, 2015
- Owen suggests the interns learn about breaking bad news to patients' families.
- 3. I Choose You Oct 8, 2015
- When Maggie gets an invitation to her ex-boyfriend's wedding, she starts to reevaluate her choices.
- 2. Walking Tall Oct 1, 2015
- April's marriage is in trouble and she struggles to face her problems.
- 1. Sledgehammer Sep 24, 2015
- Meredith adjusts to her new roommates; Jackson readies himself for April's return.