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- Season 8 overviewOct 3, 2011-May 21, 201223 episodesSeason 8 episodes1. Twenty Vicodin Oct 3, 2011
- House notices strange symptoms in a fellow inmate at the East New Jersey Correctional Facility.
- 2. Transplant Oct 10, 2011
- An unexpected visitor offers House the chance to help the Princeton Plainsboro team with a patient.
- 3. Charity Case Oct 17, 2011
- When a generous man collapses, House and Dr. Chi Park try to identify his medical disorder.
- 4. Risky Business Oct 31, 2011
- A businessman becomes ill days before signing a contract that relocates his company's labor force.
- 5. The Confession Nov 7, 2011
- A patient confesses dark secrets to his community, compromising his chances of survival.
- 6. Parents Nov 14, 2011
- The team discovers a disturbing family secret while trying to find a bone marrow match for a teen.
- 7. Dead & Buried Nov 21, 2011
- The team discovers its teenage patient isn't just being dramatic when her symptoms worsen.
- 8. Perils of Paranoia Nov 28, 2011
- During an interrogation, a prosecutor has what he thinks is a heart attack.
- 9. Better Half Jan 23, 2012
- An Alzheimer's patient participating in a drug trial suffers from a violent temper.
- 10. Runaways Jan 30, 2012
- When a homeless teenager's symptoms get worse, adult consent is required for an invasive surgery.
- 11. Nobody's Fault Feb 6, 2012
- House and the team are placed under review after a violent incident involving a patient.
- 12. Chase Feb 13, 2012
- As Chase treats Moira, a nun, they form a connection that causes Moira to question her faith.
- 13. Man of the House Feb 20, 2012
- The team notices behavioral changes in a marriage counselor who collapsed while speaking.
- 14. Love Is Blind Mar 19, 2012
- The team works to save a blind man with a mysterious illness; House's mother visits.
- 15. Blowing the Whistle Apr 2, 2012
- A sick Army veteran refuses treatment unless he is given information about his dead father.
- 16. Gut Check Apr 9, 2012
- After a fight on the ice, a 22-year-old minor league hockey player collapses and coughs up blood.
- 17. We Need the Eggs Apr 16, 2012
- The team treats a man who sheds tears of blood; House's favorite prostitute quits the business.
- 18. Body & Soul Apr 23, 2012
- The team treats a boy who wakes up from nightmares of being choked still unable to breathe.
- 19. The C-Word Apr 30, 2012
- The team treats a 6-year-old with multiple health issues; Wilson and House go on vacation.
- 20. Post Mortem May 7, 2012
- The team must convince its patient that a missing House is still calling all the shots.
- 21. Holding On May 14, 2012
- The team believes a patient's problems are both physical and psychological.
- 22. Everybody Dies May 21, 2012
- While treating a drug addicted patient, House is forced to look at his own life and personal demons.
- 23. Swan Song May 21, 2012
- A special episode looks back at the series so far, including interviews with stars and producers.