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      • Pediatric sepsis is generally considered to comprise a spectrum of disorders that result from infection by bacteria, viruses, fungi, or parasites or the toxic products of these microorganisms.
      emedicine.medscape.com › article › 972559-overview
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  2. May 9, 2023 · Pediatric definitions remain despite the new 2016 adult definitions and criteria (Sepsis-3), where “sepsis” is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection and “septic shock” is a subset of sepsis with circulatory and cellular/metabolic dysfunction associated with a higher risk of ...

  3. Specifically, the Third International Consensus Definitions for Sepsis and Septic Shock (Balamuth 2022) stresses that sepsis is a function of 4 variables, namely: threat to life. organ dysfunction (using pSOFA score) dysregulated host response. presence of highly suspected or documented infection.

  4. Pediatric Sepsis. Key Points: . Sepsis is an overwhelming and life-threatening response to an infection that can cause dysfunction of multiple organ systems. In pediatrics, diagnosing sepsis is especially challenging as children can compensate for severe illness for prolonged periods.

  5. May 25, 2022 · Consistent with the IPSCC definitions, abnormal vital signs, laboratory evidence of inflammation, and microbiological confirmation were the criteria most commonly used for the diagnosis of children with sepsis ( Fig 3A, and Supplemental Table 9 ).

    • Morin, Luc
  6. While sepsis is a serious condition at any age, it is particularly dangerous for children because their symptoms can be more difficult to detect. “The biggest difference between adult and pediatric sepsis is recognition,” says Yale Medicine pediatric intensive care doctor Sarah Kandil, MD. “A lot of symptoms we look for in sepsis, like a ...

    • 065208055
  7. May 9, 2023 · Pediatric sepsis remains an important cause of morbidity and mortality in children. This review will summarize the main aspects of the definition, the current evidence base for interventions discuss some controversial themes and point towards possible areas of improvement.

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