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  1. Explore more in Defiance

  2. Defiance is an unincorporated community and census-designated place in Saint Charles County, Missouri, United States. As of the 2020 census, the population was 159. [2] History. Defiance was struck hard in the Tornado outbreak of December 10–11, 2021, by a tornado rated EF3. One person was killed. [3] Situation.

  3. Defiance, MO is the gateway to Historic Missouri Wine Country. The Defiance area offers a spectacular destination for weekend retreats, weddings, history exploration, or recreation, and is a wonderful place to live. Located just west of the St. Louis metro area, Defiance is easy to visit and hard not to love.

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  5. May 26, 2023 · Last updated. May 26, 2023. Difficulty. Intemediate. Posted by. Susan Meyers. Category. United States. Nestled in the scenic rolling hills of Missouri lies the charming town of Defiance, a destination that offers a wealth of natural beauty, small-town charm, and exciting activities to enjoy.

  6. The Historic Daniel Boone Home, located at 1868 Hwy. F, Defiance, represents life in the early 1800s and brings the legacy of Daniel Boone to life. The Boone Home overlooks the village, a simulated town comprised of more than a dozen 19th Century buildings.

    • Diane B. Fairview Heights, IL 364 contributions. Learn about Daniel Boone, his family, and their home. The home where Daniel Boone lived a short while and died is amazing considering it was built 200+ years ago.
    • Tammy D. 6 contributions. Lovely Afternoon. Very comfortable,casual winery with nice wines, pleasant atmosphere and good music,in a peaceful settling. There are several wineries nearby in this beautiful landscape.
    • Sue D. Saint Charles, MO2 contributions. Online paddle board and kayak rentals worked well. Great, quiet park. We did the ipaddleport.com kayak and paddleboard rentals ($10/hr) and had Lake Betty to ourselves.
    • Stephen M. Lake Saint Louis, MO 127 contributions. Sunday lunch with family and friend. Visited the winery for a Sunday lunch. Food was good and reasonably priced.
  7. The Daniel Boone Home is a historic site in Defiance, Missouri, United States. The house was built by Daniel Boone's youngest son Nathan Boone, who lived there with his family until they moved further south in 1837. The Boones had moved there from Kentucky in late 1799.

  8. Jul 20, 2022 · July 20, 2022. The town of Defiance is located in the Gateway to Missouris Historic Wine Country. It’s an easy drive west of St. Louis, and is a great place to spend time with family and friends over the weekend. Defiance offers a variety of activities and events, such as weddings and history exploration.

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