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Élie Metchnikoff was a Russian-born zoologist and microbiologist who received (with Paul Ehrlich) the 1908 Nobel Prize for Physiology or Medicine for his discovery in animals of amoeba-like cells that engulf foreign bodies such as bacteria—a phenomenon known as phagocytosis and a fundamental part.
- The Editors of Encyclopaedia Britannica
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It was in Leuckart's laboratory that he made his first scientific discovery of alternation of generations (sexual and asexual) in nematodes (Chaetosomatida) and then at the University of Munich. In 1865, while at Giessen, he discovered intracellular digestion in flatworm, and this study influenced his later works.
Aug 1, 2016 · The year 2016 marks 100 years since the death of Élie Metchnikoff (1845–1916), the Russian zoologist who pioneered the study of cellular immunology and who is widely credited with the discovery of...
- David M. Underhill, Siamon Gordon, Beat A. Imhof, Gabriel Núñez, Philippe Bousso
- 2016
Feb 3, 2016 · Speakers pay tribute to his discovery of innate immunity and recite the captivating story of his famous starfish experiment in Messina, in which an implanted rose thorn evoked a vigorous macrophage reaction, suggestive to him of host immune defence.
- Siamon Gordon
- 10.1159/000443331
- 2016
- J Innate Immun. 2016 Apr; 8(3): 223-227.
Aug 25, 2016 · Metchnikoff’s hypothesis met with fierce criticisms even before the demonstration by von Behring and Kitasato of humoral (antibody-dependent) protective immunity to diphtheria toxin and the discovery of “alexines” (complement) by Ehrlich.
- Siamon Gordon
- 2016
Apr 22, 2016 · The life and work of Elie Metchnikoff are a rich source of inspiration to anybody interested in the biology and pathophysiology of myeloid cells. He made the fundamental discoveries that subsequently shaped the development of the field and that represent, still today, the basis of our knowledge.
Jul 1, 2008 · Metchnikoff discovered phagocytosis by macrophages and microphages as a critical host-defense mechanism and thus is considered the father of cellular innate immunity.
