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  2. Mar 19, 2024 · Heart Failure with Preserved Ejection Fraction (HFpEF): patients with an LVEF ≥50% with evidence of spontaneous or provokable increased left ventricular filling pressures (LVFPs), characterized by elevated natriuretic peptides or hemodynamic measurements.

    • Maheswara Satya G. Golla, Pirbhat Shams
    • 2024/01/30
    • Overview
    • What is heart failure with preserved ejection fraction?
    • What’s the difference between heart failure with preserved and reduced ejection fraction?
    • How is preserved ejection fraction treated?
    • What is the life expectancy of a person with diastolic heart failure?
    • The bottom line

    Heart failure with preserved ejection fraction (HFpEF) occurs when the heart doesn’t relax adequately. This is also known as diastolic heart failure.

    Heart failure occurs when your heart doesn’t pump enough blood to meet your body’s needs or when the heart doesn’t relax enough and pressures inside the chambers can rise. This can cause fatigue, breathing difficulties, and fluid buildup in your tissues.

    According to the Centers for Disease Control and Prevention (CDC), an estimated 6.2 million U.S. adults have heart failure. Roughly half of those people have HFpEF.

    Read on to learn about HFpEF and get the answers to common questions about treatments, outlook, and more.

    Heart failure with preserved ejection fraction (HFpEF) is a type of heart failure that occurs when the muscle in the left ventricle stiffens and is less able to relax, so the pressure inside the heart rises.

    HFpEF is usually caused by:

    •coronary artery disease

    •valvular heart disease

    •diabetes

    •obesity

    Heart failure with reduced ejection fraction (HFrEF) is also known as systolic heart failure. It also affects the left ventricle but in different ways.

    In HFrEF, the left ventricle is too weak rather than too stiff. It cannot contract properly.

    It may fill with enough blood during the cardiac cycle’s diastole phase, but it can’t pump that blood with enough force during the systole phase, so the amount of blood ejected (ejection fraction) is reduced.

    Ejection fraction is a measurement that compares the amount of blood that fills your ventricle to the amount of blood that your ventricle pumps out with each contraction.

    A typical ejection fraction is 55–70%. If your ejection fraction is below 50%, you may have HFrEF.

    If you have HFpEF, you may actually have a typical ejection fraction. That’s because there’s less blood coming into the stiffened left ventricle, but your heart can still pump that blood back out of the ventricle.

    Your doctor may prescribe diuretics to limit fluid buildup in your tissues.

    They may also prescribe treatments to manage other chronic health conditions or cardiovascular risk factors you may have.

    For example, they may prescribe medication to:

    •lower your blood pressure if you have high blood pressure

    •reduce your cholesterol level if you have high cholesterol

    •decrease your risk of blood clots if you have atrial fibrillation

    Heart failure is a potentially life threatening condition.

    A 2017 study found that all people hospitalized with heart failure survived for a median of 2.1 years. Roughly 75% of people hospitalized with HFpEF in this study passed away within 5 years.

    Cardiovascular and heart failure readmission rates were higher in those with HFrEF than those with HFpEF.

    Some people live for longer with HFpEF. Your outlook depends on:

    •how severely your heart function is affected

    •how much fluid retention you have

    Roughly half of people with heart failure have HFpEF.

    This condition reduces the amount of oxygen-rich blood that your heart delivers to other tissues and organs and increases the pressure in your heart.

    It can cause uncomfortable symptoms and raise your chances of developing potentially life threatening complications.

    It’s important to get treatment for HFpEF and other chronic health conditions you may have. Your doctor may prescribe medications and other treatments. They may also encourage you to change your lifestyle to protect your heart and overall health.

    • Heather Grey
  3. May 20, 2015. Nearly half of all patients with heart failure have a normal ejection fraction (EF). The prevalence of this syndrome, termed heart failure with preserved ejection fraction (HFpEF), continues to increase in the developed world, likely because of the increasing prevalence of common risk factors, including older age, female sex ...

  4. Jun 14, 2023 · Preserved ejection fraction (HFpEF) – also referred to as diastolic heart failure. The heart muscle contracts normally, but the ventricles do not relax as they should during ventricular filling (or when the ventricles relax). Reduced ejection fraction (HFrEF) – also referred to as systolic heart failure. The heart muscle does not contract ...

  5. May 8, 2022 · Diastolic heart failure, also known as heart failure with preserved ejection fraction (HFpEF), is a condition in which your heart’s main pumping chamber (left ventricle) becomes stiff and unable to fill properly. Diastolic heart failure is one of two kinds of left-sided heart failure.

  6. Apr 19, 2023 · Heart failure with preserved ejection fraction (HFpEF) is defined as signs and symptoms of HF with left ventricular EF (LVEF) ≥50%. Diagnosis and management of HFpEF needs multidisciplinary care involving primary care, cardiology, and HF specialists.

  7. Feb 14, 2024 · Heart failure with preserved ejection fraction (HFpEF), simply put, is when a person has a diagnosis of heart failure and their left ventricular ejection fraction (LVEF) is 50% or higher.

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