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- Pros and cons of Wegovy (semaglutide) Pros Can help you lose weight when it's used along with a nutritious diet and regular exercise Approved for use for weight loss in certain children aged 12 years and older (BMI at or above the 95th percentile) Injected once a week Cons Must inject under the skin Can cause stomach pain, nausea, and diarrhea
www.goodrx.com › wegovy › what-isWegovy (Semaglutide): Uses, Side Effects, Dosage & More - GoodRx
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What are the pros and cons of Semaglutide?
How much weight can you lose with Semaglutide?
Can wegovy (Semaglutide) help you lose weight?
Apr 22, 2023 · Health. Before and after semaglutide: 6 people on the 'game-changer' weight loss drug share its biggest pros and cons. Rachel Hosie. Apr 22, 2023, 2:00 AM PDT. Nika Steward has lost 104 pounds...
- Overview
- Is oral semaglutide as effective as the injectable version for weight loss?
- How often do you have to take semaglutide?
- Pros and cons of oral and injection semaglutide
- Where do you inject?
- Can you take semaglutide for weight loss if you do not have diabetes?
- Takeaway
Semaglutide is a drug that can be used for weight loss. Oral tablets and injections are both effective ways to ingest semaglutide.
With obesity impacting 41.9% of people in the United States, according to the Centers for Disease Control and Prevention (CDC), the weight loss drug known as semaglutide has become more popular.
This type of medication is a glucagon-like peptide-1 (GLP-1) receptor agonist, meaning it can help treat type 2 diabetes by prompting the body to make more insulin and reduce blood sugar while sending messages to the brain that you’re not hungry.
The Food and Drug Administration (FDA) has approved a few different forms of semaglutide for treating type 2 diabetes and weight loss. Wegovy and Ozempic are injectable versions, while Rybelsus is an oral tablet.
A 2021 research review looked at several clinical studies on GLP-1s and concluded that once-a-day oral semaglutide is as or more effective for weight loss than injectable versions of semaglutide, as well as in reducing A1C in people with diabetes.
That review of other recent research pointed to oral tablets having a distinguishing feature, allowing for “similar or better efficacy and similar tolerability” compared with most of the injectable GLP-1s.
However, it should be noted overall that not all semaglutides are even FDA cleared for weight loss use. And with these being newer medications, more research is needed to accurately compare the oral versus injectable semaglutides side-by-side.
However, this research looked specifically at individuals with diabetes receiving insulin which could have affected the data. More research in this area is still needed.
Semaglutide injections are generally done once a week on the same day with doses being increased after 4 weeks if necessary.
It’s important to not stop taking semaglutide without discussing it with your doctor first. If you miss a dose of Ozempic, you should inject the missed dose as soon as you remember if it’s been less than 5 days since the last dose. Otherwise, you should stick to your normal dosing schedule. You should not give yourself an extra dose or double dose for the missed shot.
If you miss a dose of Wegovy and the next dose is more than 2 days away, you should take the missed dose as soon as possible. Otherwise, you should skip the missed dose and stay on your regular schedule.
If more than 2 weeks have been missed, it’s important to contact your doctor or pharmacist. One of the labeling nuances with semaglutide is that it needs to be taken long term to be effective and maintain weight loss results.
There are oral semaglutide tablets that can be taken once a day. It’s typically recommended that these tablets be taken right when you wake up in the morning at least a half hour before eating or consuming other medications and with only a small amount of water. If you take other medications in the morning that require an empty stomach, you’ll want to discuss this with your doctor.
You can switch from one of these medications to the other with your healthcare team’s approval and guidance. The manufacturer notes that individuals can be switched from Ozempic 0.5 mg to Rybelsus 7 mg or 14 mg. Additionally, those on Rybelsus 14 mg can also be switched to Ozempic. A transition dose is currently not available.
There are benefits and drawbacks to both oral tablets and injected semaglutide.
Oral tablets:
•do not require the use of needles
•are typically taken daily
•can result in side effects like nausea, vomiting, and abdominal pain
•recommended to take on an empty stomach first thing in the morning and to not eat for 30 minutes after
Semaglutide can be injected into the upper arm, thigh, or stomach.
It can be injected in the same area of the body as insulin, but the two should not be injected next to each other.
The FDA has cleared Wegovy for weight loss in people with and without diabetes.
That does not apply to Ozempic and Rybelsus, which are not FDA cleared for weight loss and are only labeled for those with type 2 diabetes — despite the fact that doctors may choose to prescribe these medications off-label to use for weight loss alone.
Research has confirmed the weight loss benefits of semaglutide injections in individuals without diabetes.
However, it’s important to keep in mind that regardless of whether a person has diabetes, they can experience side effects from semaglutide injections.
Semaglutide is a drug that has been FDA approved as the brand name Wegovy for appetite suppression and weight loss. Semaglutide is also currently available in both oral tablet and injectable forms under other brand names for treating type 2 diabetes.
Research comparing the oral tablet and injection forms of semaglutide is still fairly new. While oral tablets offer an option without needles, they need to be taken in a very specific manner.
- Catherine Crider
Apr 3, 2024 · Semaglutide for Weight Loss . Semaglutide is a GLP-1 agonist, which mimics GLP-1, a hormone your body produces naturally. GLP-1 causes your body to release insulin, suppresses your appetite, and makes you feel full for longer. These actions together can help lead to weight loss.
Nov 17, 2023 · How They Work. Many weight loss drugs of the past have had questionable results — but semaglutide could be a game changer for the future of weight control. “These newer medications work on...
- 58 sec
Proven effectiveness: Clinical trials have demonstrated significant weight loss results with Semaglutide, with participants losing an average of 15% of their body weight. Improved Metabolic Health: Semaglutide doesn’t just support weight loss; it also helps improve overall metabolic health, reducing the risk of cardiovascular disease and ...
May 22, 2024 · A new analysis of the longest study of the obesity medication Wegovy (semaglutide) shows it can help people safely lose weight and sustain it for at least four years. The SELECT trial, which ended in 2023, showed that Wegovy can reduce the risk of heart disease, opening avenues for insurance coverage of the drug.
Jan 11, 2024 · Good for diabetes, weight loss—and more. Ozempic and Wegovy, aka semaglutide, and Mounjaro, aka tirzepatide, are FDA-approved injectable medications developed to treat adult-onset diabetes; Wegovy and Mounjaro can be prescribed for weight loss alone.
