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  2. APL is a subtype of AML that needs prompt diagnosis and treatment to prevent life-threatening complications. Learn about the different phases of APL treatment, the most important drugs, and the risk factors for relapse.

  3. Apr 2, 2024 · Acute promyelocytic leukemia (APL) is a rare blood cancer that once was a fatal illness. Now, healthcare providers consider APL a curable disease, thanks to an innovative combination of chemotherapy and non-chemotherapy drugs.

  4. Acute promyelocytic leukemia (APL) is an aggressive type of acute myeloid leukemia (AML). It happens when there are too many of the blood-forming cells called promyelocytes in the blood and bone marrow.

  5. May 7, 2015 · Because of advances in diagnosis and treatment of this disease, APL is now considered the most curable form of adult leukemia. Cure rates of 90 percent have been reported from centers specializing in APL treatment. A common symptom of APL is bleeding. This is due to reduced numbers of platelets and deficiencies in clotting factors.

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  6. Sep 25, 2018 · Studies that have investigated the treatment of APL in adults have mostly used ATRA at a total per-day dose of 45 mg/m 2, usually administered in two divided doses. A lower dose of ATRA, 25 mg/m 2, has been used in the pediatric population.

    • Afaf E G Osman, Jennifer Anderson, Jane E Churpek, Trevor N Christ, Emily Curran, Lucy A Godley, Hon...
    • 2018
  7. Acute promyelocytic leukemia (APL) is a rare cancer affecting the blood and bone marrow. It occurs primarily in middle-aged adults, but it also can affect children. Prompt diagnosis and treatment reduce symptoms long-term (remission) and often cure APL.

  8. Jun 10, 2022 · Clinical manifestations, pathologic features, and diagnosis of acute promyelocytic leukemia in adults; Differentiation syndrome associated with treatment of acute leukemia; Evaluation and management of disseminated intravascular coagulation (DIC) in adults; Gestational breast cancer: Epidemiology and diagnosis

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