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Apr 2, 2024 · Acute promyelocytic leukemia is a rare disease, so what we know about survival rates comes from clinical trials involving people with low-risk and high-risk APL. One analysis of clinical trials involving low-risk APL cases found that 99% of people were alive four years after treatment.
APL is a subtype of AML that requires prompt diagnosis and treatment to prevent life-threatening complications. Learn about the different phases of APL treatment, the drugs used, and the factors that affect the survival rate.
- Induction
- Consolidation
- Maintenance
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The induction stage aims to reduce the number of APL cells, ultimately leading to remission. Remission is when there are no or very low levels of cancerous cells. The drug all-trans retinoic acid (ATRA) can help promyelocytes mature into white blood cells by eliminating the PML-RARα protein. As a stand-alone treatment, ATRA treatment can lead to re...
Consolidation can help keep a person in remission from APL. It may also help remove any remaining APL cells. A person will generally receive the same drugs that they had during the induction phase. However, the dosage or timing of their treatment may change. The consolidation phase usually takes several monthsTrusted Sourcedepending on what treatme...
If a person has a higher risk of their APL returning, they may need further treatmentTrusted Sourceafter consolidation. In maintenance therapy, a person receives lower dosages of drugs over a longer period. The most common treatments for maintenance therapy are ATRA alone or ATRA with chemotherapy — either 6-mercaptopurine (6-MP), methotrexate, or ...
APL is a rare form of AML that affects the bone marrow and blood cells. With proper treatment, the survival rates are high, but the disease can cause serious complications. Learn more about the causes, diagnosis, and complications of APL.
May 7, 2015 · According to data from the National Cancer Institute SEER registry (from 1992 to 2007), the age-adjusted annual incidence (newly diagnosed cases) of APL was 0.23 per 100,000 persons. During that period, the average age of APL diagnosis was 44 years, which is younger than that of patients with other types of AML.
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Mar 29, 2022 · APL is a subtype of AML with a specific chromosome abnormality. It has a high cure rate with differentiating agents and chemotherapy. Learn more about the causes, diagnosis, and outlook of APL.
What is the survival rate for acute promyelocytic leukemia? At least 85–90 percent of children treated for APL are considered cured. Why choose St. Jude for your child’s acute promyelocytic leukemia treatment?
Jun 26, 2023 · Acute promyelocytic leukemia is a relatively rare and comprises about 7% to 8% of adult AML cases. Acute promyelocytic leukemia is usually seen in middle-aged people with a median age of 47 years.
