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Sir Ernst Boris Chain FRS FRSA [2] (19 June 1906 – 12 August 1979) was a German-born British biochemist and co-recipient of the Nobel Prize in Physiology or Medicine for his work on penicillin.
Sir Ernst Boris Chain was a German-born British biochemist who, with pathologist Howard Walter Florey, isolated and purified penicillin (which had been discovered in 1928 by Sir Alexander Fleming) and performed the first clinical trials of the antibiotic.
- The Editors of Encyclopaedia Britannica
Howard Walter Florey (1898–1968) and Ernst Boris Chain (1906–1979) were the scientists who followed up most successfully on Alexander Fleming’s discovery of penicillin, sharing with him the 1945 Nobel Prize in Physiology or Medicine.
Born: 19 June 1906, Berlin, Germany. Died: 12 August 1979, Mulrany, Ireland. Affiliation at the time of the award: University of Oxford, Oxford, United Kingdom. Prize motivation: “for the discovery of penicillin and its curative effect in various infectious diseases”. Prize share: 1/3.
Isolation of Penicillin at Oxford University The success of sulfa drugs sparked interest in finding other agents. At Oxford University, Ernst Chain found Fleming’s 1929 article on penicillin and proposed to his supervisor, Howard Florey, that he try to isolate the compound.
- Robert Gaynes
- 10.3201/eid2305.161556
- 2017
- Emerg Infect Dis. 2017 May; 23(5): 849-853.
Ernst Boris Chain, a German-born biochemist, shared the 1945 Nobel Prize in medicine or physiology with pathologist Howard W. Florey (1898–1968) and bacteriologist Alexander Fleming (1881–1955) “for the discovery of penicillin and its curative value in a number of infectious diseases.”
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Mar 29, 2017 · The discovery and development of penicillin by Alexander Fleming, Howard Florey, Ernst Chain, and Norman Heatley, opened a new chapter in modern medicine. The purification and characterization of penicillin resulted in identification of next generation penicillins and has led to the discovery of different classes of antibiotics, which has had a ...
