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Morbilliform drug eruption is a form of allergic reaction. It is mediated by cytotoxic T-cells and classified as a Type IV immune reaction. The target of attack may be drug, a metabolite of the drug, or a protein bonded to the drug.
A morbilliform rash is any rash that looks a lot like measles. The word “morbilliform” means measles-like. Sometimes dermatologists call them morbilliform eruptions. Many viral...
Jan 12, 2023 · Exanthematous (maculopapular) drug eruption, also called morbilliform (measles-like) drug-induced exanthem, is the most common drug hypersensitivity reaction [ 1,2 ]. It is characterized by a disseminated, and occasionally generalized, symmetric eruption of erythematous macules and/or papules ( picture 1A-B) that occur approximately one to two ...
The term morbilliform refers to a rash that looks like measles. The rash consists of macular lesions that are red and usually 2–10 mm in diameter but may be confluent in places.
Morbilliform drug eruption occurs in 1% to 5% of first-time drug users and is characterized by a widespread, maculopapular, symmetrically distributed rash. The highest drug-specific incidence is reported among patients exposed to antibiotics (1%–8%), particularly beta-lactams.
Apr 10, 2023 · Exanthematous eruptions, also described as morbilliform or erythematous maculopapular eruptions, are the most common type of drug reaction, accounting for approximately 40% of all reactions. The rash develops one day to three weeks after the offending drug is first given, although the timing can differ if previously sensitized.
Mar 4, 2022 · By definition, a morbilliform eruption is generalized and symmetric with involvement of the trunk and some portion of the extremities. The primary morphology is blanching, erythematous pink to red macules and papules that become confluent with time ( Fig. 1 ).
