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The nucleus accumbens (NAc or NAcc; also known as the accumbens nucleus, or formerly as the nucleus accumbens septi, Latin for 'nucleus adjacent to the septum') is a region in the basal forebrain rostral to the preoptic area of the hypothalamus. The nucleus accumbens and the olfactory tubercle collectively form the ventral striatum.
Oct 30, 2023 · Learn about the nucleus accumbens, a part of the ventral striatum that connects the limbic and motor systems. Find out its location, structure, connectivity and role in reward, motivation, addiction and psychiatric disorders.
- Medical Content
- 22 min
Sep 21, 2023 · Learn about the nucleus accumbens, a brain region involved in reward, motivation, and emotion. Find out its location, structure, role in the reward circuit, and associated conditions.
When rewarding stimuli are experienced, the dopaminergic mesolimbic system is activated which causes the release of dopamine to the targeted nuclei ( Small et al. 2003; Cameron et al. 2014 ). The ventral striatum, including the nucleus accumbens (NAcc), is a major substrate involved in reward ( Marche et al. 2017 ).
- 10.1007/978-3-030-81147-1_4
- 2021
Oct 18, 2019 · The nucleus accumbens (NAc) is a subcortical brain structure known primarily for its roles in pleasure, reward, and addiction. Despite less focus on the NAc in pain research, it also plays a large role in the mediation of pain and is effective as a source of analgesia.
- Haley N Harris, Yuan B Peng
- 10.4103/1673-5374.266909
- 2020
- Neural Regen Res. 2020 Apr; 15(4): 597-605.
The nucleus accumbens (NAc) is a key node of the brain’s circuitry that is responsible for translating motivation into action. It has been implicated in playing critical roles in virtually all forms of adaptive and pathological motivated behaviors.
A target of increasing interest is the nucleus accumbens (NAc), which has long been studied as a key brain region mediating a variety of behaviors, including reward and satisfaction.
