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Aug 6, 2023 · Adopting a step-by-step diagnostic approach incorporating modern imaging machinery and techniques can facilitate early diagnosis and treatment. When evaluating patients with suspected osteomyelitis, the initial imaging step is typically plain radiography.
- Dushyant G. Dobaria, Harris L. Cohen
- 2023/08/06
- UTHSC, Univ of Tenn HSC
Apr 1, 2016 · MRI is the best imaging modality for establishing the diagnosis of osteomyelitis as it can demonstrate bone marrow oedema, confirm the presence of abscesses and delineate extraosseous disease spread. If MRI is contraindicated or unavailable, nuclear medicine studies and CT are useful alternatives.
- Yu Jin Lee, Sufi Sadigh, Kshitij Mankad, Nikhil Kapse, Gajan Rajeswaran
- 10.21037/qims.2016.04.01
- 2016
- 2016/04
- Diagnosis
- Terminology
- Epidemiology
- Pathology
- Radiographic Features
- Treatment and Prognosis
- Differential Diagnosis
The pathological diagnosis of osteomyelitis requires a reliable tissue sample from which bacteria are isolated, along with histological findings of inflammatory cells and osteonecrosis 21. Given low culture yields (~35%), pathological testing often results in false-negative results. Osteomyelitis can be diagnosed on MRI in cases of suspected infect...
Reactive bone marrow edema and osteitis are recommended to be avoided in cases of infection as these can occur in non-infectious conditions, e.g. inflammatory arthritis 21. Acute osteomyelitis is where symptoms are present for <2 weeks and chronic osteomyelitis is where symptoms are present for >4 weeks 21.
Osteomyelitis can occur at any age. In those without specific risk factors, it is particularly common between the ages of 2-12 years and is more common in males (M:F of 3:1) 6.
In most instances, osteomyelitis results from hematogenous spread, although direct extension from trauma and/or ulcers is relatively common (especially in the feet of diabetic patients). In the initial stages of infection, bacteria multiply, triggering a localized inflammatory reaction that results in localized cell death. With time, the infection ...
MRI has the highest accuracy to detect osteomyelitis with a sensitivity of 90% and specificity of ~80% 21. In some instances, imaging features are specific to a region or a particular type of infection, for example: 1. subperiosteal abscess 2. Brodie abscess 3. Pott puffy tumor 4. sclerosing osteomyelitis of Garré Below are the general features of ...
Treatment of osteomyelitis is typical with intravenous antibiotics, often for extended periods. If a collection, sequestrum, or involucrumis present, drainage and/or surgical debridement is often necessary. Amputation is performed after failure of medical therapy or when the infection is life-threatening. Complications include 1: 1. sinus tract for...
General imaging differential considerations include: 1. Charcot joint 2. metastases 3. primary bone neoplasm 3.1. Ewing sarcoma 3.2. osteosarcoma 3.3. lymphoma 3.4. multiple myeloma 4. Langerhans cell histiocytosis (LCH)
Jul 9, 2024 · The benefits and limitations of plain x-rays, magnetic resonance imaging (MRI), computed tomography (CT), positron emission tomography (PET)-CT, other nuclear modalities, and ultrasonography for the diagnosis of osteomyelitis will be reviewed here.
Osteomyelitis is usually clinically diagnosed with support from imaging and laboratory findings. Bone biopsy and microbial cultures offer definitive diagnosis.
Magnetic resonance imaging is the most sensitive and most specific imaging modality for the detection of osteomyelitis and provides superb anatomic detail and more accurate information of the extent of the infectious process and soft tissues involved.
Magnetic resonance imaging is the imaging modality of choice for suspected osteomyelitis, although plain film radiography is often done initially.13. In adult patients hospitalized with...
