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Biomechanical pain pathways in osteoarthritis. Biography. Rachel E. Miller, PhD, is an Associate Professor in the Department of Internal Medicine, Division of Rheumatology at RUSH University Medical Center.
Understanding how inflammation may contribute to, and modify pain in OA will be instrumental in identifying new druggable targets for analgesic therapies. In this narrative review, we discuss recent insights into inflammatory mechanisms in OA pain.
Pain in OA is complex and multi-factorial, modified by genetic, psychological, and environmental determinants. Patients struggle to self-describe pain with just ‘intensity’, and describe numerous types of pain that vary in duration, depth, type of occurrence, impact, and rhythm 18.
- 10.1016/j.cger.2021.11.013
- 2022/05
CCL2 and CCR2 regulate pain-related behaviour and early gene expression in post-traumatic murine osteoarthritis but contribute little to chondropathy. JM Zarebska, A Chanalaris, C Driscoll, A...
Mar 12, 2024 · When It Hurts to Hope will show you the middle ground between burying your longings and overindulging them. Rachel Miller offers encouragement and practical advice on how to honor God and honor your desires at the same time, sharing tools for readers to be emotionally and spiritually healthy.
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- Rachel Miller
Associate Professor in the Division of Rheumatology; Bioengineer and scientist with a focus on musculoskeletal research. Currently investigating the development of pain in osteoarthritis ...
- 339 followers
Apr 29, 2023 · Here, the authors show that inhibiting a mechanically-sensitive ion channel expressed by nociceptors reduces pain behaviors in mouse models of joint pain.
