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  1. Aquagenic wrinkling of the palms is characterised by the appearance of a palmar eruption of white or translucent papules and plaques following brief exposure to water. Patients may report an uncomfortable tight, burning, or itchy sensation during an eruption.

  2. Mar 13, 2019 · Patients affected with aquagenic wrinkling of the palms (AWP) complain that upon exposure to water, they note reddening of the skin of the palms, and eventually notice a whitening and thickening of the palms resembling waterlogging. Patients may notice the sensation of burning, stinging, or tingling localized to the palms.

  3. Mar 1, 2022 · Aquagenic pruritus is a skin condition that causes severe itching after contact with water. Treatment involves finding the right therapy to manage your symptoms.

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  5. Nov 22, 2019 · Physical examination found normal palm appearance with slightly hyperkeratotic fingertips before water immersion (Fig 1) and excessive wrinkling and rapid development of white flat-topped papules with papillomatous appearance 3 to 4 minutes after water exposure (Fig 2, A and B).

    • Nikifor K. Konstantinov, Elena Obreshkova
    • 10.1016/j.jdcr.2019.09.022
    • 2019
    • JAAD Case Rep. 2019 Dec; 5(12): 1068-1070.
  6. Aug 2, 2017 · White papules occur in puberty and are concentrated on the margins of palms and soles, which suggests a contributory effect of trauma and pressure. The papules are persistent and there is no association between water exposure and the development of skin lesions.

    • Magdalena Żychowska, Aleksandra Batycka-Baran, Jacek Szepietowski, Wojciech Baran
    • 10.5114/ada.2017.69321
    • 2017
    • 2017/08
  7. Dec 1, 2018 · Clinical findings. After brief (minutes of) exposure to water, the patient experiences exaggerated wrinkling of the palms along with white, edematous papules that may coalesce into plaques. Upon removal from water, her skin changes typically resolve in less than 1 hour with drying of the skin.

  8. Up to 80% of people with cystic fibrosis experience aquagenic wrinkling of the palms. 1 Aquagenic wrinkling explained Aquagenic wrinkling was only first described in literature in the year 1974. 1 It is characterized by a rapid formation of swollen, white plaques on the palms and soles when exposed to water.

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