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  1. Publish with us. Policies and ethics. This chapter is based on the research and experience in treating signs of aging with a scientific multimodality approach over more than 23 years. Wrinkles are part of any anti-aging treatment, surgical rejuvenation procedures, and many plastic surgeries.

  2. A randomized, controlled comparative study of the wrinkle reduction benefits of a cosmetic niacinamide/peptide/retinyl propionate product regimen vs. a prescription 0·02% tretinoin product regimen - PMC. Journal List. Wiley-Blackwell Online Open. PMC2841824. As a library, NLM provides access to scientific literature.

    • J.J.J. Fu, G.G. Hillebrand, P. Raleigh, J. Li, M.J. Marmor, V. Bertucci, P.E. Grimes, S.H. Mandy, M....
    • 10.1111/j.1365-2133.2009.09436.x
    • 2010
    • Br J Dermatol. 2010 Mar; 162(3): 647-654.
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  4. Jan 1, 2022 · Current research reveals that collagen use could result in a reduction of wrinkles, rejuvenation of skin, and reversal of skin aging , which may improve skin hydration and elasticity . However, the available evidence regarding types of collagen or its mechanism of action, duration to produce desired results and side effects have not been ...

    • Hend Al-Atif
    • 2022/02
    • 10.5826/dpc.1201a18
  5. PMID: 32090898. DOI: 10.1016/j.jmbbm.2020.103694. Abstract. Skin wrinkling, especially in the facial area, is a prominent sign of aging and is a growing area of research aimed at developing cosmetics and dermatological treatments.

    • Y. Zhao, B. Feng, J. Lee, N. Lu, D.M. Pierce
    • 2020
    • Chronological Age
    • Ethnicity
    • Gender
    • Geography
    • Solar Exposure
    • Seasonal Changes
    • Air Pollution and Smoking
    • Sleeping Position
    • Wrinkling at Body Sites Other Than The Face

    Chronological age is generally the best predictor of a person’s wrinkle severity . However, the age-related changes in wrinkling occur very slowly and are essentially undetectable from one year to the next. To best assess changes in facial skin wrinkles over time, individuals need to be tracked over several years, even decades in a longitudinal stu...

    Ethnic differences in facial skin wrinkling have been reported previously. Darker skin types generally show less wrinkling in sun-exposed areas than lighter skin types, due to the photoprotection afforded by more epidermal melanin in the darker skin. Timilshina et al. compared facial skin wrinkling in 240 subjects of either Aryan- (Caucasian) or M...

    It generally accepted that the age of onset and severity of facial skin wrinkling differ between the sexes with men bearing most of the burden. Both differences in hormonal state, lifestyle, and sun protection habits play a role. Luebberding used 3D imaging combined with clinical grading to compare facial wrinkling in 150 Caucasian men and 50 women...

    Previous studies have shown that the severity of facial skin wrinkling increases as latitude decreases, presumably reflecting the higher total lifetime sun exposure at lower latitudes . More recently, Gao et al. compared the pattern of lines on the hands of Chinese men and women living in either Sanya (18°N, low latitude) or Shenyang (41°N, high l...

    Kimlin and Guo captured detailed lifetime sun exposure histories on 180 subjects, both men and women, across a wide age range (18–83). They measured facial wrinkling on every subject using the VISIA Complexion Analysis System®. They observed a nonlinear relationship between lifetime sun exposure and facial skin wrinkling with younger subjects havi...

    Several studies have focused on the seasonal and circadian changes in facial wrinkling. A year-long study was conducted to determine the effect of inherent chronologic variation on the appearance of facial wrinkling . The study followed 12 Caucasian females (age 40–65) over a 54-week period with standardized imaging and clinical grading three times...

    The effect of indoor and outdoor air pollution on skin aging is a growing concern, especially in urban areas. Polyaromatic hydrocarbons and nano-sized particulates can be inhaled or attached directly to and get absorbed into the skin putting oxidative stress on cells and tissues. Two papers out of Jean Krutman’s lab reported results of cross-sectio...

    Does sleeping on one’s side or stomach cause sleep creases on the face? Should people sleep on their backs to avoid hours of creasing their face against the pillow? Lateral oblique forehead lines (wrinkles that run vertically on the left and right sides of the forehead) have been thought to be “sleeping lines.” However, De Boulle and Turkmani repor...

    Much of the focus in skin wrinkling research and treatment intervention has been on facial wrinkles, primarily periorbital or crow’s feet wrinkles around the eye. With new consumer understanding on the importance and concern for wrinkling at other body sites, attention is now being given to areas that had previously been largely ignored such as the...

    • Greg Hillebrand
    • dermscience@yahoo.com
  6. The current literature does show some methodological shortcomings, and further research is required to truly establish microneedling as an evidence-based therapeutic option for treating scars, wrinkles and other skin conditions. Keywords: Microneedling; Percutaneous collagen induction; Review; Scars; Skin rejuvenation.

  7. link.springer.com › referenceworkentry › 10Wrinkles | SpringerLink

    Wrinkles. Paradi Mirmirani. Reference work entry. 62 Accesses. Download reference work entry PDF. Human skin, like all other organs of the body undergoes changes with aging. In addition to intrinsic or chronologic changes, environmental exposure can be a major cause of skin damage and wrinkling.

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