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  1. Howard Walter Florey (1898–1968) and Ernst Boris Chain (1906–1979) were the scientists who followed up most successfully on Alexander Fleming’s discovery of penicillin, sharing with him the 1945 Nobel Prize in Physiology or Medicine.

  2. The Nobel Prize in Physiology or Medicine 1945 was awarded jointly to Sir Alexander Fleming, Ernst Boris Chain and Sir Howard Walter Florey "for the discovery of penicillin and its curative effect in various infectious diseases".

  3. In 1928, at St. Mary's Hospital, London, Alexander Fleming discovered penicillin. This discovery led to the introduction of antibiotics that greatly reduced the number of deaths from infection. Howard W. Florey, at the University of Oxford working with Ernst B. Chain, Norman G. Heatley and Edward P. Abraham, successfully took penicillin from ...

  4. The Nobel Prize in Physiology or Medicine 1945 was awarded jointly to Sir Alexander Fleming, Ernst Boris Chain and Sir Howard Walter Florey "for the discovery of penicillin and its curative effect in various infectious diseases"

  5. Jun 15, 2024 · Sir Ernst Boris Chain was a German-born British biochemist who, with pathologist Howard Walter Florey, isolated and purified penicillin (which had been discovered in 1928 by Sir Alexander Fleming) and performed the first clinical trials of the antibiotic.

    • The Editors of Encyclopaedia Britannica
  6. en.wikipedia.org › wiki › Ernst_ChainErnst Chain - Wikipedia

    In 1939, he joined Howard Florey to investigate natural antibacterial agents produced by microorganisms. This led him and Florey to revisit the work of Alexander Fleming , who had described penicillin nine years earlier.

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  8. Apr 22, 2004 · The second item, which flags a story that he develops, reads: “There are four people at the heart of the penicillin story: Fleming, Florey, Heatley, and Ernst Chain.”

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