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Jun 22, 2021 · Establishing a diagnosis of aplastic anemia (AA) can be challenging, but it is absolutely critical to appropriate management, especially differentiating between acquired and inherited forms of the disease.
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To diagnose AA, there must be at least two of the following, haemoglobin concentration (Hb) <100 g/L, platelet count <50 × 109/L and neutrophil count <1.5 × 109/L. Reticulocyte count is useful in delineating the severity of AA. The majority (70%–80%) of cases are idiopathic.
Jul 17, 2023 · Explain the treatment and management options available for aplastic anemia. Summarize interprofessional team strategies for enhancing care coordination and communication to advance treatment of aplastic anemia and improve outcomes.
- Christine A. Moore, Koyamangalath Krishnan
- 2023/07/17
In 2023, in response to long-standing member interest, ASH approved a plan to develop clinical practice guidelines about aplastic anemia. Like other ASH guidelines, these new guidelines will be developed using methods that meet the highest standards for rigor and trust.
Nov 11, 2017 · In patients with suspected AA, rapid and accurate diagnosis and concomitant supportive care are critical. Historically, immunosuppressive therapy (IST) and bone marrow transplantation (BMT) in eligible patients have been the mainstay of AA treatment [1].
- Scott A. Peslak, Timothy Olson, Daria V. Babushok, Daria V. Babushok
- 10.1007/s11864-017-0511-z
- 2017
- 2017/11/11
Mar 16, 2017 · Treatment strategy in patients with acquired aplastic anemia. Patients are stratified according to whether or not they have an HLA-identical sibling. In young patients (<40 years) with a matched donor, allogeneic BMT is first-line therapy.
Apr 8, 2022 · Summary. Aplastic anemia is a form of pancytopenia, most often idiopathic. May present with sequelae of neutropenia (infections), anemia (fatigue, pallor, dyspnea, tachycardia), or thrombocytopenia (bleeding, bruising). Laboratory findings may include leukopenia, neutropenia, anemia, and thrombocytopenia.
