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  1. Oct 3, 2023 · By Christina Sterbenz. October 3, 2023. Claire S. Riley, MD. Even though scientists don’t yet know the cause of stiff person syndrome, they do know that being startled or going through emotional distress can trigger its symptoms. Some clues, however, do exist.

  2. Stiff Person Syndrome (SPS) has been divided into different types. The differences are based on the clinical and physical manifestations. The causes and treatments of each type may differ. There are varying expert perspectives about the details of each type of SPS.

  3. Apr 25, 2024 · Stiff person syndrome is a rare neurological movement disorder characterized by sudden and painful proximal and axial muscle stiffness and spasms. These muscle contractions can lead to difficulty walking, increased risk of falls and fractures, and other consequences that impair the mental stability and quality of life of people with SPS.

    • What Is Stiff Person Syndrome?
    • Who Does Stiff Person Syndrome Affect?
    • Is Stiff Person Syndrome painful?
    • Is Stiff Person Syndrome Life threatening?
    • Can Stiff Person Syndrome Be Treated?
    • Further Reading

    Stiff person syndrome (SPS) is a very rare, long-term condition that causes painful muscle spasms and debilitating muscle stiffness. Scientists don't yet fully understand stiff person syndrome, but it's thought to be an autoimmune disorder - where your immune system attacks healthy cells - involving the messages sent between your brain and spinal c...

    Those most likely people to have stiff person syndrome are: 1. Born female. 2. Between 30 and 60 years of age - although it can also affect children and the elderly. 3. Those with another autoimmune disease - such as type 1 diabetes, vitiligo, or coeliac disease. This condition is so rare that it is hard to know how many people suffer from it. It i...

    When Céline Dion first took to social media to share her diagnosis, she explained that her muscle spasms affected every aspect of her daily life, making normal activities like walking a struggle. Céline has since cancelled her 'Courage World Tour' in order to build back her strength. Muscle stiffness causes aches and pains that can feel better or w...

    Death associated with this neurological disorder is rare. When it does happen, it's not a direct result of stiff person syndrome, but rather its complications. These complications could include severe injury, wound infections, or blood clots caused by immobility issues.

    Stiff person syndrome is a chronic condition, meaning you have it for the rest of your life. While there is no cure, treatment can help to ease symptoms, improve quality of life, slow its progression, and reduce the risk of other health complications. The first step is getting a diagnosis, but as the condition is so uncommon that it's easy to mista...

  4. May 22, 2023 · SPSD diagnosis was defined as clinical SPSD manifestations confirmed by an autoimmune neurologist and seropositivity for high‐titer GAD65‐IgG (>20.0 nmol/L), glycine‐receptor‐IgG or amphiphysin‐IgG, and/or confirmatory electrodiagnostic studies (essential if seronegative).

    • 10.1002/acn3.51791
    • 2023/07
  5. Summary. Stiff person syndrome (SPS) is a rare, progressive syndrome that affects the nervous system, specifically the brain and spinal cord. Symptoms may include extreme muscle stiffness, rigidity and painful spasms in the trunk and limbs, severely impairing mobility. Spasms can generate enough force to fracture bone.

  6. Aug 8, 2022 · Stiff person syndrome (SPS) is a rare neuroimmunological disorder that is associated with multiple symptoms and varying levels of disability. SPS is highly heterogeneous and a broad spectrum of signs and symptoms are captured under the umbrella of SPS spectrum disorders (SPSD).

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