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  1. my.clevelandclinic.org › health › diseasesStiff Person Syndrome (SPS): What It Is, Symptoms & Treatment

    Stiff person syndrome (SPS) is a rare autoimmune neurological disorder that causes muscle stiffness in your trunk and abdomen (the middle part of your body). Over time, you may also develop stiffness (rigidity) and spasms in your legs and other muscles.

  2. www.osmosis.org › answers › stiff-person-syndromeStiff Person Syndrome: What Is It, Causes, Diagnosis, and ...

    Apr 25, 2024 · Stiff person syndrome is a rare neurological movement disorder characterized by sudden and painful proximal and axial muscle stiffness and spasms. These muscle contractions can lead to difficulty walking, increased risk of falls and fractures, and other consequences that impair the mental stability and quality of life of people with SPS.

  3. rarediseases.org › rare-diseases › stiff-person-syndromeStiff Person Syndrome - Symptoms, Causes, Treatment | NORD

    Jul 11, 2023 · Stiff person syndrome (SPS) is a rare acquired neurological disorder that most often causes progressive muscle stiffness (rigidity) and repeated episodes of painful muscle spasms. Muscular rigidity often fluctuates (i.e., grows worse and then improves) and usually occurs along with the muscle spasms.

  4. www.americanbrainfoundation.org › diseases › stiffStiff Person Syndrome - American Brain Foundation

    Stiff person syndrome (SPS) is a rare neurologic disorder characterized by episodes of painful muscle spasms, progressive muscle stiffness in the trunk and limbs, and a heightened sensitivity to stimuli such as noise, touch, or stress.

  5. www.verywellmind.com › stiff-person-syndrome-7090364What Is Stiff-Person Syndrome (SPS)? - Verywell Mind

    Jan 3, 2023 · Stiff-person syndrome is a neurological disorder that is characterized by muscle stiffness and painful muscle spasms. It is a rare condition that only affects one or two persons in every million people.

  6. www.uptodate.com › contents › stiff-person-syndromeStiff-person syndrome - UpToDate

    May 21, 2024 · Stiff-person syndrome (SPS, formerly called stiff-man syndrome) is an uncommon disorder characterized by progressive muscle stiffness, rigidity, and spasm involving the axial muscles, resulting in severely impaired ambulation [1,2].

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  8. www.hopkinsmedicine.org › stiff-person-syndromeJohns Hopkins Stiff Person Syndrome Center

    Stiff person syndrome is a rare disease affecting only one or two people per million. It commonly causes muscle stiffness and painful spasms that worsen over time. They can be triggered by a variety of things including sudden movement, cold temperature or unexpected loud noises. Learn more about stiff person syndrome. Watch on YouTube -

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