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  1. Apr 25, 2024 · Stiff person syndrome is a rare neurological movement disorder characterized by sudden and painful proximal and axial muscle stiffness and spasms. These muscle contractions can lead to difficulty walking, increased risk of falls and fractures, and other consequences that impair the mental stability and quality of life of people with SPS.

  2. Sep 28, 2022 · Stiff-person syndrome (SPS, formerly called stiff-man syndrome) is an uncommon disorder characterized by progressive muscle stiffness, rigidity, and spasm involving the axial muscles, resulting in severely impaired ambulation [ 1,2 ].

  3. There are 3 types of stiff-person syndrome: autoimmune, paraneoplastic, and idiopathic. Stiff-person syndrome affects the CNS but causes progressive muscle stiffness, rigidity, and spasms, mainly in the trunk and abdomen.

    • What Is Stiff Person Syndrome?
    • Who Does Stiff Person Syndrome Affect?
    • Is Stiff Person Syndrome painful?
    • Is Stiff Person Syndrome Life threatening?
    • Can Stiff Person Syndrome Be Treated?
    • Further Reading

    Stiff person syndrome (SPS) is a very rare, long-term condition that causes painful muscle spasms and debilitating muscle stiffness. Scientists don't yet fully understand stiff person syndrome, but it's thought to be an autoimmune disorder - where your immune system attacks healthy cells - involving the messages sent between your brain and spinal c...

    Those most likely people to have stiff person syndrome are: 1. Born female. 2. Between 30 and 60 years of age - although it can also affect children and the elderly. 3. Those with another autoimmune disease - such as type 1 diabetes, vitiligo, or coeliac disease. This condition is so rare that it is hard to know how many people suffer from it. It i...

    When Céline Dion first took to social media to share her diagnosis, she explained that her muscle spasms affected every aspect of her daily life, making normal activities like walking a struggle. Céline has since cancelled her 'Courage World Tour' in order to build back her strength. Muscle stiffness causes aches and pains that can feel better or w...

    Death associated with this neurological disorder is rare. When it does happen, it's not a direct result of stiff person syndrome, but rather its complications. These complications could include severe injury, wound infections, or blood clots caused by immobility issues.

    Stiff person syndrome is a chronic condition, meaning you have it for the rest of your life. While there is no cure, treatment can help to ease symptoms, improve quality of life, slow its progression, and reduce the risk of other health complications. The first step is getting a diagnosis, but as the condition is so uncommon that it's easy to mista...

  4. Stiff person syndrome (SPS) is a rare autoimmune disorder of the central nervous system consisting of fluctuating, progressive rigidity of truncal and proximal limbs due to continuous co-contracture of agonist and antagonist muscles, with episodic painful muscle spasms. 1,2 It is a clinic diagnosis and can be further delineated into classic SPS ...

  5. Stiff person syndrome is a rare disease affecting only one or two people per million. It commonly causes muscle stiffness and painful spasms that worsen over time. They can be triggered by a variety of things including sudden movement, cold temperature or unexpected loud noises.

  6. Stiff person syndrome (SPS) is a rare neurologic disorder characterized by episodes of painful muscle spasms, progressive muscle stiffness in the trunk and limbs, and a heightened sensitivity to stimuli such as noise, touch, or stress. 30-50. Age range SPS is typically diagnosed. 2x. Number of women affected vs. men. Fewer than 5,000.

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