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In 1963 the American Society of Anesthesiologists (ASA) adopted the five-category physical status classification system; a sixth category was later added. These are: Healthy person. Mild systemic disease. Severe systemic disease. Severe systemic disease that is a constant threat to life.
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- A normal healthy patient. Healthy, non-smoking, no or minimal alcohol use.
- A patient with mild systemic disease. Mild diseases only without substantive functional limitations. Examples include (but not limited to): current smoker, social alcohol drinker, pregnancy, obesity (30 < BMI < 40), well-controlled DM/HTN, mild lung disease.
- A patient with severe systemic disease. Substantive functional limitations; One or more moderate to severe diseases. Examples include (but not limited to): poorly controlled DM or HTN, COPD, morbid obesity (BMI ≥40), active hepatitis, alcohol dependence or abuse, implanted pacemaker, moderate reduction of ejection fraction, ESRD undergoing regularly scheduled dialysis, premature infant PCA < 60 weeks, history (>3 months) of MI, CVA, TIA, or CAD/stents.
- A patient with severe systemic disease that is a constant threat to life. Examples include (but not limited to): recent ( < 3 months) MI, CVA, TIA, or CAD/stents, ongoing cardiac ischemia or severe valve dysfunction, severe reduction of ejection fraction, sepsis, DIC, ARD or ESRD not undergoing regularly scheduled dialysis.
May 29, 2023 · Systemic inflammatory response syndrome (SIRS) is an exaggerated defense response of the body to a noxious stressor (infection, trauma, surgery, acute inflammation, ischemia or reperfusion, or malignancy, to name a few) to localize and then eliminate the endogenous or exogenous source of the insult.
- Rebanta K. Chakraborty, Bracken Burns
- 2023/05/29
- 2019
Jan 27, 2016 · Chronic inflammatory systemic diseases (CIDs) like rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis and many others are a burden to humans because of life-long debilitating illness, increased mortality and high costs for therapy and care.
- Rainer H Straub, Carsten Schradin
- 10.1093/emph/eow001
- 2016
- Evol Med Public Health. 2016; 2016(1): 37-51.
Feb 29, 2024 · The American Society of Anesthesiologists (ASA) Physical Status Classification System is a risk-stratifying system used mainly by anesthesiologists to help predict preoperative risks; it has been...
Jul 29, 2020 · In this review, we report on treatment recommendations for four classes of CNS inflammation resulting from systemic disease: (1) rheumatologic diseases with CNS involvement, (2) inflammatory adverse effects of common pharmacological therapies, (3) postviral inflammatory syndromes, and (4) autoimmune diseases resulting from immunodeficiency ...
Systemic sclerosis is a rare chronic disease of unknown cause characterized by diffuse fibrosis and vascular abnormalities in the skin, joints, and internal organs (especially the esophagus, lower gastrointestinal tract, lungs, heart, and kidneys).