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  1. May 1, 2024 · Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

  2. Sep 27, 2019 · The most common potential side effect is soreness at or around the injection site. Other potential side effects include mild headache, loss of appetite among children, and feeling tired. These side effects usually last 1 or 2 days.

    • On this Page
    • About Hepatitis A
    • Vaccine Information Statements
    • Available Vaccines
    • Common Side Effects
    • Hepatitis A Vaccines
    • More Information
    • Report Possible Adverse Events To VAERS
    • A Closer Look at the Safety Data
    • How CDC Monitors Vaccine Safety

    Hepatitis A is a highly contagious liver infection caused by the hepatitis A virus. It can range from a mild illness lasting a few weeks to a severe illness lasting several months. Although rare, hepatitis A can cause death in some people. Hepatitis A usually spreads when a person unknowingly ingests the virus from food, drinks, or objects contaminated by stool (poop) from an infected person. Hepatitis A can also spread from close personal contact with an infected person such as through sex or caring for someone who is ill.

    Most adults with hepatitis A have symptoms that include fatigue, loss of appetite, stomach pain, nausea, and jaundice (skin becomes yellow). It usually resolves within 2 months of infection. Most children younger than 6 years of age do not have symptoms or have an unrecognized infection.

    Learn more about hepatitis A.

    There are safe and effective vaccines than can protect against hepatitis A.

    Vaccine Information Statements (VISs) are information sheets produced by CDC that explain both the benefits and risks of a vaccine.

    Who Should Get Hepatitis A Vaccine

    CDC recommends 2 doses of hepatitis A vaccine, given at least 6 months apart for: •All children, beginning at 1 year •People with unstable housing or experiencing homelessness •People who are at increased risk for infection •People who are at increased risk for complications from hepatitis A

    Talk with your healthcare provider about vaccines.

    They can answer questions and offer advice based on your specific health needs. •Anyone who wants protection against hepatitis A For more information, see Who should get vaccinated against hepatitis A. Top of Page

    Manufacturer Package Inserts

    Open All Close All Single antigen hepatitis A vaccines Combination vaccine with hepatitis A Top of Page

    Severe allergic reactions following vaccination are rare, but can be life threatening.

    Symptoms of a severe allergic reaction can include hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, and weakness.

    Common Side Effects

    •Swelling, tenderness, redness, warmth, or a hard lump where the shot was given

    •Low fever

    •General ill feeling

    •Nausea

    •Loss of appetite

    •Hepatitis A Questions and Answers for the Public

    Learn more about the hepatitis A virus and the vaccines that provide protection.

    •Who Should not Get Vaccinated?

    Some people should not get certain vaccines or should wait before getting them. Read the CDC guidelines for each vaccine.

    •Hepatitis A Vaccine – ACIP Recommendations and Guidance

    Official guidance on hepatitis A vaccine from the Advisory Committee on Immunization Practices (ACIP).

    The Vaccine Adverse Event Reporting System (VAERS) is an early warning system, co-managed by CDC and FDA, that monitors for potential vaccine safety problems.

    Healthcare providers and vaccine manufacturers are required by law to report certain adverse events following vaccination to VAERS; patients and caregivers can also submit reports.

    •Since hepatitis A vaccine was licensed in 1995 through 2005, approximately 50 million doses were distributed in the United States. In that same time, VAERS received 6,136 reports of adverse events among people who received the hepatitis A vaccine (by itself or with other vaccines). The most common events reported were fever, injection site reaction, rash, and headache. The review of these reports was unable to determine a causal relationship between the vaccine and the reported events. The review of VAERS reports were similar to the original safety review for Havrix and Vaqta. During prelicensure clinical trials, the most commonly reported side effects for Havrix and Vaqta in both adults and children included injection site reactions, such as soreness, tenderness, pain, warmth, and headache. Children 11-25 months who received Havrix were also reported to experience irritability, drowsiness, and loss of appetite.

    Source: Prevention of Hepatitis A Through Active or Passive Immunization: Recommendations of the Advisory Committee on Immunization Practices. [MMWR. 2006]

    •A 2004 study of Vaqta among a large group of California patients showed no health problems linked to vaccination. More than 49,000 doses of Hepatitis A vaccine were given to the patients; 15,000 were given to children younger than 18 years of age.

    Source: A Post-Licensure Evaluation of the Safety of Inactivated Hepatitis A Vaccine (VAQTA, Merck) in Children and Adults. [Vaccine. 2004]

    •A 2-year review of Hepatitis A vaccine safety using VAERS data found no safety problems when the vaccine began to be used as part of the routine immunization schedule in the United States.

    Source: Two-year Review of Hepatitis A Vaccine Safety: Data from the Vaccine Adverse Event Reporting System (VAERS). [Vaccine. 1998]

    CDC and FDA monitor the safety of vaccines after they are approved or authorized. If a problem is found with a vaccine, CDC and FDA will inform health officials, health care providers, and the public.

    CDC uses 3 systems to monitor vaccine safety:

    •The Vaccine Adverse Event Reporting System (VAERS): an early warning system, co-managed by CDC and FDA, to monitor for potential vaccine safety problems. Anyone can report possible vaccine side effects to VAERS.

    •The Vaccine Safety Datalink (VSD): a collaboration between CDC and 13 healthcare organizations that conducts vaccine safety monitoring and research.

  3. Oct 27, 2023 · The most common side effect of the hepatitis A vaccine involves soreness at the site of injection. This reaction may present with: a hard bump. tenderness. warmth. skin redness or...

  4. Are there any dangers or side effects associated with the vaccine? 3 min read. The hepatitis A vaccine can prevent hepatitis A, which can be a serious (although rarely fatal) liver...

  5. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

  6. Jan 11, 2024 · Possible side effects. There are no serious side effects from hepatitis A vaccines. The most common side effect is soreness in the area around the shot site.

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