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Nitric Oxide, also known as NO, is a natural signaling molecule produced in the arteries, brain and many other organs in the body. In its natural state, NO is a very unstable gaseous molecule that lasts for only a second or less after being produced inside cells.
Prevent unwanted blood clotting and obstruction to blood flow in arteries. Anti-inflammatory action in arteries to maintain a healthy arterial inner lining without cholesterol plaque buildup. Promotes learning, memory and information recall in the brain.
Louis Joseph Ignarro (born May 31, 1941) is an American pharmacologist. For demonstrating the signaling properties of nitric oxide, he was co-recipient of the 1998 Nobel Prize in Physiology or Medicine with Robert F. Furchgott and Ferid Murad .
We designed a series of chemical, biochemical and pharmacological experiments to detect and quantify NO and, against all odds, demonstrated in 1986 that EDRF is nitric oxide. This was the first demonstration that NO can and does exist in mammalian cells.
In 1983, my laboratory set out to determine whether or not mammalian cells can produce either nitric oxide or a nitro compound that could be metabolized to nitric oxide. A separate project in the laboratory was to study endothelium-dependent vasorelaxation and to attempt to identify the mysterious “EDRF” (endothelium derived relaxing factor ...
May 31, 2011 · Louis J. Ignarro The Nobel Prize in Physiology or Medicine 1998 . Born: 31 May 1941, Brooklyn, NY, USA . Affiliation at the time of the award: University of California School of Medicine, Los Angeles, CA, USA . Prize motivation: “for their discoveries concerning nitric oxide as a signalling molecule in the cardiovascular system” Prize share ...
Robert F. Furchgott, Louis J. Ignarro and Ferid Murad for their discoveries concerning “nitric oxide as a signalling molecule in the cardiovascular system”. Nitric oxide (NO) is a gas that transmits signals in the organism.
