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Megaloblastic anemia is a type of macrocytic anemia. An anemia is a red blood cell defect that can lead to an undersupply of oxygen. [1] Megaloblastic anemia results from inhibition of DNA synthesis during red blood cell production. [2] When DNA synthesis is impaired, the cell cycle cannot progress from the G2 growth stage to the mitosis (M) stage.
Thiếu máu do thiếu vitamin B12, trong đó thiếu máu ác tính là một dạng đặc biệt, [1] là một bệnh trong đó không đủ tế bào hồng cầu được tạo ra do thiếu vitamin B 12. [2] Triệu chứng ban đầu phổ biến nhất là cảm thấy mệt mỏi.
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May 27, 2022 · Megaloblastic anemia is a type of vitamin deficiency anemia that happens when you don’t get enough vitamin B12 and/or vitamin B9 (folate). Healthcare providers treat megaloblastic anemia with vitamin B12 and B9 supplements.
Feb 14, 2022 · Megaloblastic anemia is a type of blood cell deficiency with larger than normal red blood cells and enlarged and abnormal red blood cell precursors (megaloblasts) in the bone marrow. This type of anemia often develops due to vitamin B12 (cobalamin) deficiency or vitamin B9 (folate) deficiency.
Megaloblastic anemia is a type of anemia caused by deficiencies in folic acid or vitamin B12. Folic acid and vitamin B12 are essential for DNA synthesis, and thus the production of healthy red blood cells.
Key Points. Megaloblastic anemias result most often from deficiencies of vitamin B12 and folate. Ineffective hematopoiesis affects all cell lines but particularly red blood cells.
May 17, 2024 · A comprehensive description of pathophysiology of disease, the sensitivity and specificity of anti-intrinsic factor and anti-parietal cell antibodies, situations under which methylmalonyl-CoA (MMA) and homocysteine (HC) tested, importance of the transcobalamins in B12 metabolism and tests to monitor response to B12 therapy are discussed in quest...
